anti-SCUBE2 antibody
Key features and details
- 产品描述:
- 反应物种:
- 预测物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
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Brand:
CAT.NO. : ARG57560
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes SCUBE2 |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Rat |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | SCUBE2 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide (17 aa) within aa. 480-530 of Human SCUBE2. |
| 偶联标记 | Un-conjugated |
| 別名 | Signal peptide, CUB and EGF-like domain-containing protein 2; CEGF1; CEGB1; Protein CEGP1; CEGP1 |
应用说明
| 应用建议 |
| ||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
| 阳性对照 | Daudi cells. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | PBS and 0.02% Sodium azide. |
| 抗菌剂 | 0.02% Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # Q9NQ36 Human Signal peptide, CUB and EGF-like domain-containing protein 2 |
|---|---|
| 基因名称 | SCUBE2 |
| 全名 | signal peptide, CUB domain, EGF-like 2 |
| 生物功能 | Lipid-binding protein required for SHH long-range signaling by binding to the dually lipid-modified SHH (ShhNp) and by promoting ShhNp mobilization, solubilization and release from the cell membrane (PubMed:22902404, PubMed:22677548). Acts by enhancing the proteolytic processing (shedding) of the lipid-modified N- and C- terminal of ShhNp at the cell surface (PubMed:24522195). Synergizes with DISP1 to increase SHH secretion (PubMed:22902404). Probable cell surface coreceptor for VEGFR2 involved in VEGFR2-mediated angiogenesis (PubMed:27834687). [UniProt] |
| 预测分子量 | 110 kDa |
检测图片 (3)
ARG57560 anti-SCUBE2 antibody ICC/IF image
Immunocytochemistry: Daudi cells stained with ARG57560 anti-SCUBE2 antibody at 20 µg/ml dilution.
ARG57560 anti-SCUBE2 antibody WB image
Western blot: Daudi cell lysate stained with ARG57560 anti-SCUBE2 antibody at 1 µg/ml dilution in the absence and the presence of blocking peptide.
ARG57560 anti-SCUBE2 antibody ICC/IF image
Immunofluorescence: Daudi cells stained with ARG57560 anti-SCUBE2 antibody at 20 µg/ml dilution
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