anti-SCYL2 antibody
CAT.NO. : ARG40026
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概述
产品描述 | Rabbit Polyclonal antibody recognizes SCYL2 |
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反应物种 | Hu, Ms, Rat |
应用 | ICC/IF, WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | SCYL2 |
抗原物种 | Human |
抗原 | Recombinant fusion protein corresponding to aa. 1-300 of Human SCYL2 (NP_060458.3). |
偶联标记 | Un-conjugated |
別名 | SCY1-like protein 2; Coated vesicle-associated kinase of 104 kDa; CVAK104 |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
阳性对照 | Rat brain and Mouse brain | ||||||
实际分子量 | 104 kDa |
属性
形式 | Liquid |
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纯化 | Affinity purified. |
缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
抗菌剂 | 0.02% Sodium azide |
稳定剂 | 50% Glycerol |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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基因名称 | SCYL2 |
全名 | SCY1-like, kinase-like 2 |
生物功能 | Component of AP2-containing clathrin coated structures at the plasma membrane or of endocytic coated vesicles. Probable serine/threonine-protein kinase that phosphorylates, in vitro, the beta2-subunit of the plasma membrane adapter complex AP2 and other proteins in presence of poly-L-lysine. Has no detectable kinase activity in vitro. May regulate clathrin-dependent trafficking between the TGN and/or the endosomal system. [UniProt] |
细胞定位 | Cytoplasm, perinuclear region. Cytoplasmic vesicle, clathrin-coated vesicle. Golgi apparatus, trans-Golgi network membrane. Endosome membrane. Note=According to PubMed:15809293, plasma membrane-associated in clathrin-coated vesicles. According to PubMed:16914521, colocalizes to the trans-Golgi network (TGN) and to endosomal membranes with clathrin, transferrin and plasma membrane adapter AP1 and AP3 complexes. [UniProt] |
预测分子量 | 104 kDa |
翻译后修饰 | According to PubMed:15809293, autophosphorylated in presence of poly-L-lysine. [UniProt] |
