anti-Semaphorin 4D antibody [A8]

Key features and details

  • 产品描述: Mouse Monoclonal antibody [A8] recognizes Semaphorin 4D
  • 反应物种: Hu, Ms
  • 应用: FACS, ICC/IF
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 克隆号: A8
  • 同位型: IgG1, kappa
  • 靶点名称: Semaphorin 4D
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG56008
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Product Details
概述
产品描述Mouse Monoclonal antibody [A8] recognizes Semaphorin 4D
反应物种Hu, Ms
应用FACS, ICC/IF
宿主Mouse
克隆Monoclonal
克隆号A8
同位型IgG1, kappa
靶点名称Semaphorin 4D
抗原物种Human
抗原PHA stimulated Human peripheral blood lymphocytes.
偶联标记Un-conjugated
別名CD100; GR3; CD antigen CD100; M-sema-G; BB18; C9orf164; SEMAJ; Semaphorin-4D; A8; coll-4
应用说明
应用建议
应用推荐稀释比
FACS0.5 - 1 µg/10^6 cells
ICC/IF0.5 - 1 µg/ml
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purification with Protein G.
缓冲液PBS (pH 7.4), 0.05% Sodium azide and 0.1 mg/ml BSA
抗菌剂0.05% Sodium azide
稳定剂0.1 mg/ml BSA
浓度0.2 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 10507 Human SEMA4D

GeneID: 20354 Mouse SEMA4D

Swiss-port # O09126 Mouse Semaphorin-4D

Swiss-port # Q92854 Human Semaphorin-4D

基因名称SEMA4D
全名sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
生物功能Cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. Promotes reorganization of the actin cytoskeleton and plays a role in axonal growth cone guidance in the developing central nervous system. Regulates dendrite and axon branching and morphogenesis. Promotes the migration of cerebellar granule cells and of endothelial cells. Plays a role in the immune system; induces B-cells to aggregate and improves their viability (in vitro). Promotes signaling via SRC and PTK2B/PYK2, which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade. Interaction with PLXNB1 mediates activation of RHOA. [UniProt]
细胞定位Cell surface
预测分子量96 kDa
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