anti-SETMAR antibody

Key features and details

  • 产品描述: Goat Polyclonal antibody recognizes SETMAR
  • 反应物种: Hu
  • 预测物种: Cow
  • 应用: WB
  • 宿主: Goat
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: SETMAR
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG63243
US$ Please choose
US$ Please choose
Size:
Trail, Bulk size or Custom requests Please contact us
*产品价格可能会有所调整,请以品牌方官网实时更新的价格为准,以确保准确性。
Product Details
概述
产品描述Goat Polyclonal antibody recognizes SETMAR
反应物种Hu
预测物种Cow
应用WB
宿主Goat
克隆Polyclonal
同位型IgG
靶点名称SETMAR
抗原物种Human
抗原RWQKCVDCNGSYFD
偶联标记Un-conjugated
別名HsMar1; SET domain and mariner transposase fusion protein; EC 3.1.-.-; EC 2.1.1.43; Mar1; METNASE; Histone-lysine N-methyltransferase SETMAR; Metnase
应用说明
应用建议
应用推荐稀释比
WB1 - 3 µg/ml
应用说明WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
缓冲液Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
抗菌剂0.02% Sodium azide
稳定剂0.5% BSA
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 6419 Human SETMAR

Swiss-port # Q53H47 Human Histone-lysine N-methyltransferase SETMAR

背景介绍This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
研究领域Gene Regulation antibody
预测分子量78 kDa
翻译后修饰Methylated. Methylation regulates activity in DNA decatenation.
Phosphorylated at Ser-508 by CHEK1 and dephosphorylated by protein phosphatase 2A/PP2A. Phosphorylation at Ser-508 is enhanced by DNA damage and promotes recruitment to damaged DNA. It stimulates DNA repair and impairs replication fork restart.
检测图片 (1)
  • ARG63243 anti-SETMAR antibody WB image

    Western Blot: Daudi lysate (RIPA buffer, 30µg total protein per lane) stained with ARG63243 anti-SETMAR antibody at 2 µg/ml dilution.

New Products
Get in touch with AREX
Name:*
Tel/Phone:*
Company:*
Email:*
Inquiry:
Captcha*
Submitting your email information means that you are willing to receive email information from AREX regarding technology, applications, products, and events. By clicking on the 'unsubscribe' button in the email or by contacting info@arexbio.com You can unsubscribe at any time by sending an email. Regarding your data usage information, please refer to our privacy policy.
© AREX 2024. All Rights Reserved. | 浙ICP备2024113709号-3 Sitemap