anti-SGLT1 antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG10837
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes SGLT1 |
|---|---|
| 反应物种 | Hu, Ms, Rat, Bb, Mk, Pig |
| 应用 | ICC/IF, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | SGLT1 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide around aa. 402-422 of Human SGLT1. |
| 偶联标记 | Un-conjugated |
| 別名 | NAGT; D22S675; SGLT1; Sodium/glucose cotransporter 1; High affinity sodium-glucose cotransporter; Solute carrier family 5 member 1 |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | Tris, HCl / Glycine buffer (pH 7.4 - 7.8), Hepes, 0.02% Sodium azide, 30% Glycerol and 0.5% BSA. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 30% Glycerol and 0.5% BSA |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | SLC5A1 |
| 全名 | solute carrier family 5 (sodium/glucose cotransporter), member 1 |
| 背景介绍 | This gene encodes a member of the sodium-dependent glucose transporter (SGLT) family. The encoded integral membrane protein is the primary mediator of dietary glucose and galactose uptake from the intestinal lumen. Mutations in this gene have been associated with glucose-galactose malabsorption. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012] |
| 生物功能 | Actively transports glucose into cells by Na(+) cotransport with a Na(+) to glucose coupling ratio of 2:1. Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na(+)/glucose cotransporter arranged in series along kidney proximal tubules. [UniProt] |
| 预测分子量 | 73 kDa |
| 翻译后修饰 | N-glycosylation is not necessary for the cotransporter function. |
检测图片 (3)
ARG10837 anti-SGLT1 antibody IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded Baboon small intestine stained with ARG10837 anti-SGLT1 antibody at 1:50 dilution. DAB (brown) staining and Hematoxylin QS (blue) counterstain. 10X magnification.
ARG10837 anti-SGLT1 antibody WB image
Western blot: Purified Human SGLT1 protein stained with ARG10837 anti-SGLT1 antibody at 1:500 dilution. Apparent MW is 70 - 74 kDa.
ARG10837 anti-SGLT1 antibody IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded Baboon small intestine stained with ARG10837 anti-SGLT1 antibody at 1:50 dilution. DAB (brown) staining and Hematoxylin QS (blue) counterstain. 40X magnification.
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