anti-SH3BP1 antibody

Key features and details

  • 产品描述: Goat Polyclonal antibody recognizes SH3BP1
  • 反应物种: Hu
  • 应用: ICC/IF, IHC-P, WB
  • 宿主: Goat
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: SH3BP1
  • 抗原物种: Human
  • 抗原: C-PQPRPRSLASETN
  • Brand:
CAT.NO. : ARG63425
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Product Details
概述
产品描述Goat Polyclonal antibody recognizes SH3BP1
反应物种Hu
应用ICC/IF, IHC-P, WB
宿主Goat
克隆Polyclonal
同位型IgG
靶点名称SH3BP1
抗原物种Human
抗原C-PQPRPRSLASETN
偶联标记Un-conjugated
別名SH3 domain-binding protein 1; 3BP-1; ARHGAP43
应用说明
应用建议
应用推荐稀释比
ICC/IFAssay - dependent
IHC-P0.3 - 1 µg/ml
WB1 - 3 µg/ml
应用说明IHC-P: Antigen Retrieval: Microwaved tissue section in Citrate buffer (pH 6.0).
WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
缓冲液Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
抗菌剂0.02% Sodium azide
稳定剂0.5% BSA
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 23616 Human SH3BP1

Swiss-port # Q9Y3L3 Human SH3 domain-binding protein 1

基因名称SH3BP1
全名SH3-domain binding protein 1
生物功能Binds differentially to the SH3 domains of certain proteins of signal transduction pathways. This protein binds preferentially to the ABL1 proto-oncogene, SRC and GRB2. Shows GAP activity for Rac-related proteins but not for Rho- or Ras-related proteins. It inhibits PDGF-induced membrane ruffling mediated by Rac (By similarity). [UniProt]
研究领域Signaling Transduction antibody
预测分子量76 kDa
检测图片 (2)
  • ARG63425 anti-SH3BP1 antibody WB image

    Western Blot: Human Brain lysate (RIPA buffer, 35 µg total protein per lane) stained with ARG63425 anti-SH3BP1 antibody at 1 µg/ml dilution.

  • ARG63425 anti-SH3BP1 antibody IHC-P image

    Immunohistochemistry: paraffin embedded Human Kidnay. Cytoplasmic staining of lymphocytes A) in the interstitial parenchyma of the kidney. B) in a glomerulus of the kidney. (Microwaved antigen retrieval with citrate buffer pH 6) stained with ARG63425 anti-SH3BP1 antibody at 0.3 µg/ml dilution followed by HRP-staining.

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