anti-SHB antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG55768
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes SHB |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS, IHC-P, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | SHB |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide corresponding to aa. 250-290 of Human SHB. |
| 偶联标记 | Un-conjugated |
| 別名 | SH2 domain-containing adapter protein B; bA3J10.2 |
应用说明
| 应用建议 |
| ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||
| 阳性对照 | HepG2 |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purification with Protein A and immunogen peptide. |
| 缓冲液 | PBS and 0.09% (W/V) sodium azide. |
| 抗菌剂 | 0.09% (W/V) sodium azide. |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # Q15464 Human SH2 domain-containing adapter protein B |
|---|---|
| 基因名称 | SHB |
| 全名 | Src homology 2 domain containing adaptor protein B |
| 生物功能 | Adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components. May play a role in angiogenesis by regulating FGFR1, VEGFR2 and PDGFR signaling. May also play a role in T-cell antigen receptor/TCR signaling, interleukin-2 signaling, apoptosis and neuronal cells differentiation by mediating basic-FGF and NGF-induced signaling cascades. May also regulate IRS1 and IRS2 signaling in insulin-producing cells. [UniProt] |
| 细胞定位 | Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Associates with membrane lipid rafts upon TCR stimulation |
| 预测分子量 | 55 kDa |
| 翻译后修饰 | Phosphorylated upon PDGFRA, PDGFRB, TCR, IL2 receptor, FGFR1 or VEGFR2 activation. |
检测图片 (3)
ARG55768 anti-SHB antibody IHC-P image
Immunohistochemistry: Paraffin-embedded Human small intestine tissue stained with ARG55768 anti-SHB antibody at 1:25 dilution.
ARG55768 anti-SHB antibody WB image
Western blot: 35 µg of HepG2 cell lysate stained with ARG55768 anti-SHB antibody at 1:1000 dilution.
ARG55768 anti-SHB antibody FACS image
Flow Cytometry: HepG2 cells stained with ARG55768 anti-SHB antibody (right histogram) at 1:25 dilution or isotype control antibody (left histogram), followed by incubation with Alexa Fluor® 488 labelled secondary antibody.
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