anti-SHMT1 antibody [26E5]

Key features and details

  • 产品描述: Mouse Monoclonal antibody [26E5] recognizes SHMT1
  • 反应物种: Hu
  • 应用: ICC/IF, WB
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 克隆号: 26E5
  • 同位型: IgG1, kappa
  • 靶点名称: SHMT1
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG57163
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Product Details
概述
产品描述Mouse Monoclonal antibody [26E5] recognizes SHMT1
反应物种Hu
应用ICC/IF, WB
宿主Mouse
克隆Monoclonal
克隆号26E5
同位型IgG1, kappa
靶点名称SHMT1
抗原物种Human
抗原Recombinant fragment around aa. 1-483 of Human SHMT1
偶联标记Un-conjugated
別名EC 2.1.2.1; SHMT; CSHMT; Serine methylase; Glycine hydroxymethyltransferase; Serine hydroxymethyltransferase, cytosolic
应用说明
应用建议
应用推荐稀释比
ICC/IFAssay-dependent
WBAssay-dependent
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purification with Protein A.
缓冲液PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol.
抗菌剂0.02% Sodium azide
稳定剂10% Glycerol
浓度1 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 6470 Human SHMT1

Swiss-port # P34896 Human Serine hydroxymethyltransferase, cytosolic

基因名称SHMT1
全名serine hydroxymethyltransferase 1 (soluble)
背景介绍This gene encodes the cytosolic form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one-carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. A pseudogene of this gene is located on the short arm of chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
生物功能Interconversion of serine and glycine. [UniProt]
预测分子量53 kDa
检测图片 (2)
  • ARG57163 anti-SHMT1 antibody [26E5] ICC/IF image

    Immunofluorescence: Hep3B cells line stained with ARG57163 anti-SHMT1 antibody [26E5] at 1:100 (Green).

    DAPI (Blue) for nucleus staining.

  • ARG57163 anti-SHMT1 antibody [26E5] WB image

    Western blot: 40 µg of 1) A549, 2) HeLa, 3) NIH-3T3, and 4) LnCaP cell lysates stained with ARG57163 anti-SHMT1 antibody [26E5] at 1:1000.

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