anti-SHMT1 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes SHMT1
  • 反应物种: Hu, Ms, Rat
  • 应用: ICC/IF, IHC-P, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: SHMT1
  • 抗原物种: Human
  • 抗原: Recombinant protein sequence corresponding to the c-terminal 180 a.a. of Human SHMT1.
  • Brand:
CAT.NO. : ARG55531
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes SHMT1
反应物种Hu, Ms, Rat
应用ICC/IF, IHC-P, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称SHMT1
抗原物种Human
抗原Recombinant protein sequence corresponding to the c-terminal 180 a.a. of Human SHMT1.
偶联标记Un-conjugated
別名EC 2.1.2.1; SHMT; CSHMT; Serine methylase; Glycine hydroxymethyltransferase; Serine hydroxymethyltransferase, cytosolic
应用说明
应用建议
应用推荐稀释比
ICC/IF1:50 - 1:200
IHC-P1:50 - 1:200
WB1:500 - 1:2000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照HepG2
属性
形式Liquid
纯化Affinity purification with immunogen.
缓冲液PBS (pH7.3), 0.02% Sodium azide and 50% Glycerol
抗菌剂0.02% Sodium azide
稳定剂50% Glycerol
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 20425 Mouse SHMT1

GeneID: 6470 Human SHMT1

Swiss-port # P34896 Human Serine hydroxymethyltransferase, cytosolic

Swiss-port # P50431 Mouse Serine hydroxymethyltransferase, cytosolic

基因名称SHMT1
全名serine hydroxymethyltransferase 1 (soluble)
背景介绍This gene encodes the cytosolic form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one-carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. A pseudogene of this gene is located on the short arm of chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
生物功能Interconversion of serine and glycine. [UniProt]
研究领域Metabolism antibody; Signaling Transduction antibody
预测分子量53 kDa
检测图片 (1)
  • ARG55531 anti-SHMT1 antibody WB image

    Western blot: HepG2 cell lysate stained with ARG55531 anti-SHMT1 antibody.

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