anti-SIK2 antibody
CAT.NO. : ARG57588
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概述
产品描述 | Rabbit Polyclonal antibody recognizes SIK2 |
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反应物种 | Hu, Ms, Rat |
应用 | WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | SIK2 |
抗原物种 | Human |
抗原 | Recombinant protein of Human SIK2. |
偶联标记 | Un-conjugated |
別名 | SNF1LK2; Serine/threonine-protein kinase SIK2; QIK; LOH11CR1I; Qin-induced kinase; Salt-inducible kinase 2; SIK-2; EC 2.7.11.1; Serine/threonine-protein kinase SNF1-like kinase 2 |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
阳性对照 | HepG2 |
属性
形式 | Liquid |
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纯化 | Affinity purified. |
缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
抗菌剂 | 0.02% Sodium azide |
稳定剂 | 50% Glycerol |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | Swiss-port # Q8CFH6 Mouse Serine/threonine-protein kinase SIK2 Swiss-port # Q9H0K1 Human Serine/threonine-protein kinase SIK2 |
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基因名称 | SIK2 |
全名 | salt-inducible kinase 2 |
生物功能 | Phosphorylates 'Ser-794' of IRS1 in insulin-stimulated adipocytes, potentially modulating the efficiency of insulin signal transduction. Inhibits CREB activity by phosphorylating and repressing TORCs, the CREB-specific coactivators. [UniProt] |
预测分子量 | 104 kDa |
翻译后修饰 | Phosphorylated at Thr-175 by STK11/LKB1 in complex with STE20-related adapter-alpha (STRADA) pseudo kinase and CAB39. Acetylation at Lys-53 inhibits kinase activity. Deacetylated by HDAC6. [UniProt] |
