anti-SIK2 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes SIK2
  • 反应物种: Hu, Ms, Rat
  • 应用: WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: SIK2
  • 抗原物种: Human
  • 抗原: Recombinant protein of Human SIK2.
  • Brand:
CAT.NO. : ARG57588
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes SIK2
反应物种Hu, Ms, Rat
应用WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称SIK2
抗原物种Human
抗原Recombinant protein of Human SIK2.
偶联标记Un-conjugated
別名SNF1LK2; Serine/threonine-protein kinase SIK2; QIK; LOH11CR1I; Qin-induced kinase; Salt-inducible kinase 2; SIK-2; EC 2.7.11.1; Serine/threonine-protein kinase SNF1-like kinase 2
应用说明
应用建议
应用推荐稀释比
WB1:500 - 1:2000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照HepG2
属性
形式Liquid
纯化Affinity purified.
缓冲液PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol.
抗菌剂0.02% Sodium azide
稳定剂50% Glycerol
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 23235 Human SIK2

GeneID: 235344 Mouse SIK2

Swiss-port # Q8CFH6 Mouse Serine/threonine-protein kinase SIK2

Swiss-port # Q9H0K1 Human Serine/threonine-protein kinase SIK2

基因名称SIK2
全名salt-inducible kinase 2
生物功能Phosphorylates 'Ser-794' of IRS1 in insulin-stimulated adipocytes, potentially modulating the efficiency of insulin signal transduction. Inhibits CREB activity by phosphorylating and repressing TORCs, the CREB-specific coactivators. [UniProt]
预测分子量104 kDa
翻译后修饰Phosphorylated at Thr-175 by STK11/LKB1 in complex with STE20-related adapter-alpha (STRADA) pseudo kinase and CAB39.

Acetylation at Lys-53 inhibits kinase activity. Deacetylated by HDAC6. [UniProt]
检测图片 (1)
  • ARG57588 anti-SIK2 antibody WB image

    Western blot: 25 µg of HepG2 cell lysate stained with ARG57588 anti-SIK2 antibody at 1:1000 dilution.

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