anti-SLA Class II DR antibody [2E9/13]

Key features and details

  • 产品描述: Mouse Monoclonal antibody [2E9/13] recognizes SLA Class II DRThis antibody recognizes SLA DR molecules which are expressed on all B cells, antigen presenting cells and on certain subsets of resting and activated T cells.Mouse anti Pig SLA Class II DR antibody, clone 289/13 reacts with lymphocytes from all outbred and miniature pigs so far tested, suggesting that it recognizes a monomorphic determinant of Porcine SLA DR.The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In pigs, this is referred to as the swine leukocyte antigen (SLA) region. There are 3 major MHC class II proteins encoded by the SLA which are SLA DP, SLA DQ and SLA DR.Mouse anti Pig SLA class II Dr, clone 2E9/13 immunoprecipitates a heterodimer composed of two polypeptides of 28 and 35kD from NP-40 extracts of biotin surface-labelled Porcine peripheral blood mononuclear cells.Clone 2E9/13 is reported to inhibit the mixed lymphocyte reaction and T cell stimulation induced by African swine fever virus and staphylococcal enterotoxin B (Bullido et al. 1997).
  • 反应物种: Bov, Pig
  • 应用: FACS, IHC-Fr, IP
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 克隆号: 2E9/13
  • 同位型: IgG2b
  • 靶点名称: SLA Class II DR
  • 抗原物种: Pig
  • Brand:
CAT.NO. : ARG22658
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Product Details
概述
产品描述Mouse Monoclonal antibody [2E9/13] recognizes SLA Class II DR
This antibody recognizes SLA DR molecules which are expressed on all B cells, antigen presenting cells and on certain subsets of resting and activated T cells.
Mouse anti Pig SLA Class II DR antibody, clone 289/13 reacts with lymphocytes from all outbred and miniature pigs so far tested, suggesting that it recognizes a monomorphic determinant of Porcine SLA DR.
The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In pigs, this is referred to as the swine leukocyte antigen (SLA) region. There are 3 major MHC class II proteins encoded by the SLA which are SLA DP, SLA DQ and SLA DR.
Mouse anti Pig SLA class II Dr, clone 2E9/13 immunoprecipitates a heterodimer composed of two polypeptides of 28 and 35kD from NP-40 extracts of biotin surface-labelled Porcine peripheral blood mononuclear cells.
Clone 2E9/13 is reported to inhibit the mixed lymphocyte reaction and T cell stimulation induced by African swine fever virus and staphylococcal enterotoxin B (Bullido et al. 1997).
反应物种Bov, Pig
应用FACS, IHC-Fr, IP
宿主Mouse
克隆Monoclonal
克隆号2E9/13
同位型IgG2b
靶点名称SLA Class II DR
抗原物种Pig
抗原Porcine monocytes.
偶联标记Un-conjugated
別名SLA-DRA1; SLA-DRA2; SLA-DR-alpha
应用说明
应用建议
应用推荐稀释比
FACS1:25 - 1:200
IHC-FrAssay-dependent
IPAssay-dependent
应用说明FACS: Use 10 µl of the suggested working dilution to 10^6 cells in 100 µl.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purification with Protein A.
缓冲液PBS and 0.09% Sodium azide.
抗菌剂0.09% Sodium azide
浓度1 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
基因名称SLA-DRA
全名MHC class II DR-alpha
检测图片 (1)
  • ARG22658 anti-SLA Class II DR antibody [2E9/13] FACS image

    Flow Cytometry: Pig peripheral blood lymphocytes stained with ARG22658 anti-SLA Class II DR antibody [2E9/13] followed by Goat anti-Mouse IgG (FITC).

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