anti-SLA Class II DR antibody [2E9/13]
CAT.NO. : ARG22658
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概述
产品描述 | Mouse Monoclonal antibody [2E9/13] recognizes SLA Class II DR This antibody recognizes SLA DR molecules which are expressed on all B cells, antigen presenting cells and on certain subsets of resting and activated T cells. Mouse anti Pig SLA Class II DR antibody, clone 289/13 reacts with lymphocytes from all outbred and miniature pigs so far tested, suggesting that it recognizes a monomorphic determinant of Porcine SLA DR. The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In pigs, this is referred to as the swine leukocyte antigen (SLA) region. There are 3 major MHC class II proteins encoded by the SLA which are SLA DP, SLA DQ and SLA DR. Mouse anti Pig SLA class II Dr, clone 2E9/13 immunoprecipitates a heterodimer composed of two polypeptides of 28 and 35kD from NP-40 extracts of biotin surface-labelled Porcine peripheral blood mononuclear cells. Clone 2E9/13 is reported to inhibit the mixed lymphocyte reaction and T cell stimulation induced by African swine fever virus and staphylococcal enterotoxin B (Bullido et al. 1997). |
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反应物种 | Bov, Pig |
应用 | FACS, IHC-Fr, IP |
宿主 | Mouse |
克隆 | Monoclonal |
克隆号 | 2E9/13 |
同位型 | IgG2b |
靶点名称 | SLA Class II DR |
抗原物种 | Pig |
抗原 | Porcine monocytes. |
偶联标记 | Un-conjugated |
別名 | SLA-DRA1; SLA-DRA2; SLA-DR-alpha |
应用说明
应用建议 |
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应用说明 | FACS: Use 10 µl of the suggested working dilution to 10^6 cells in 100 µl. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化 | Purification with Protein A. |
缓冲液 | PBS and 0.09% Sodium azide. |
抗菌剂 | 0.09% Sodium azide |
浓度 | 1 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
基因名称 | SLA-DRA |
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全名 | MHC class II DR-alpha |
