anti-SLC10A1 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes SLC10A1
  • 反应物种: Hu, Ms, Rat
  • 应用: IHC-P, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: SLC10A1
  • 抗原物种: Human
  • 抗原: aa. 141-154 (YSRGIYDGDLKDKV) of Human SLC10A1.
  • Brand:
CAT.NO. : ARG10599
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes SLC10A1
反应物种Hu, Ms, Rat
应用IHC-P, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称SLC10A1
抗原物种Human
抗原aa. 141-154 (YSRGIYDGDLKDKV) of Human SLC10A1.
偶联标记Un-conjugated
別名Sodium/bile acid cotransporter; Cell growth-inhibiting gene 29 protein; Na; Sodium/taurocholate cotransporting polypeptide; Solute carrier family 10 member 1; NTCP
应用说明
应用建议
应用推荐稀释比
IHC-P0.5 - 1 µg/ml
WB0.5 - 1 µg/ml
应用说明Antigen Retrieval for IHC-P: steamed with pH 6 citrate buffer.

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Affinity purification with immunogen.
缓冲液PBS, 0.025% Sodium azide and 2.5% BSA.
抗菌剂0.025% Sodium azide
稳定剂2.5% BSA
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 20493 Mouse SLC10A1

GeneID: 24777 Rat SLC10A1

GeneID: 6554 Human SLC10A1

基因名称SLC10A1
全名solute carrier family 10 (sodium/bile acid cotransporter), member 1
背景介绍The protein encoded by this gene belongs to the sodium/bile acid cotransporter family, which are integral membrane glycoproteins that participate in the enterohepatic circulation of bile acids. Two homologous transporters are involved in the reabsorption of bile acids; the ileal sodium/bile acid cotransporter with an apical cell localization that absorbs bile acids from the intestinal lumen, bile duct and kidney, and the liver-specific sodium/bile acid cotransporter, represented by this protein, that is found in the basolateral membranes of hepatocytes. Bile acids are the catabolic product of cholesterol metabolism, hence this protein is important for cholesterol homeostasis. [provided by RefSeq, Oct 2011]
生物功能The hepatic sodium/bile acid uptake system exhibits broad substrate specificity and transports various non-bile acid organic compounds as well. It is strictly dependent on the extracellular presence of sodium. [UniProt]
预测分子量38 kDa
检测图片 (2)
  • ARG10599 anti-SLC10A1 antibody IHC-P image

    Immunohistochemistry: Human liver cancer tissue stained with ARG10599 anti-SLC10A1 antibody.

  • ARG10599 anti-SLC10A1 antibody WB image

    Western blot: 1) Rat liver and 2) Rat brain lysate stained with ARG10599 anti-SLC10A1 antibody.

参考文献

Integrated 16 S rRNA gene sequencing and serum metabolomics approaches to decipher the mechanism of Qingre Lidan decoction in the treatment of cholestatic liver injury

WB / Mouse

Yang Chang et al.
J Pharm Biomed Anal.,  (2023)

publication_link

 

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