anti-SLC27A4 / FATP4 antibody
CAT.NO. : ARG42874
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概述
产品描述 | Rabbit Polyclonal antibody recognizes SLC27A4 / FATP4 |
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反应物种 | Hu |
应用 | ICC/IF, IHC-P, IP, WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | SLC27A4 / FATP4 |
抗原物种 | Human |
抗原 | Recombinant protein of Human SLC27A4 / FATP4. |
偶联标记 | Un-conjugated |
別名 | ACSVL4; EC 6.2.1.-; FATP-4; Fatty acid transport protein 4; IPS; FATP4; Solute carrier family 27 member 4; Long-chain fatty acid transport protein 4 |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||||||
阳性对照 | K562 | ||||||||||
实际分子量 | ~ 70 kDa |
属性
形式 | Liquid |
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纯化 | Affinity purified. |
缓冲液 | 50 mM Tris-Glycine (pH 7.4), 150 mM NaCl, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA. |
抗菌剂 | 0.01% Sodium azide |
稳定剂 | 40% Glycerol and 0.05% BSA |
浓度 | Batch dependent |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | Swiss-port # Q6P1M0 Human Long-chain fatty acid transport protein 4 |
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基因名称 | SLC27A4 |
全名 | solute carrier family 27 (fatty acid transporter), member 4 |
背景介绍 | This gene encodes a member of a family of fatty acid transport proteins, which are involved in translocation of long-chain fatty acids cross the plasma membrane. This protein is expressed at high levels on the apical side of mature enterocytes in the small intestine, and appears to be the principal fatty acid transporter in enterocytes. Clinical studies suggest this gene as a candidate gene for the insulin resistance syndrome. Mutations in this gene have been associated with ichthyosis prematurity syndrome. [provided by RefSeq, Apr 2010] |
生物功能 | Involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane. Appears to be the principal fatty acid transporter in small intestinal enterocytes. Plays a role in the formation of the epidermal barrier. Required for fat absorption in early embryogenesis. Has acyl-CoA ligase activity for long-chain and very-long-chain fatty acids (VLCFAs). Indirectly inhibits RPE65 via substrate competition and via production of VLCFA derivatives like lignoceroyl-CoA. Prevents light-induced degeneration of rods and cones (By similarity). [UniProt] |
细胞定位 | Membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane. [UniProt] |
预测分子量 | 72 kDa |
