anti-SLC29A3 / ENT3 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes SLC29A3 / ENT3
  • 反应物种: Ms, Rat
  • 预测物种: Hu
  • 应用: IHC-P, WB
  • 特异性: This SLC29A3 / ENT antibody is predicted to not cross-react with other SLC29 proteins.
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: SLC29A3 / ENT3
  • Brand:
CAT.NO. : ARG43456
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes SLC29A3 / ENT3
反应物种Ms, Rat
预测物种Hu
应用IHC-P, WB
特异性This SLC29A3 / ENT antibody is predicted to not cross-react with other SLC29 proteins.
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称SLC29A3 / ENT3
抗原物种Human
抗原A 19 amino acid peptide within aa. N-terminal of Human SLC29A3 / ENT3.
偶联标记Un-conjugated
Protein Full nameEquilibrative nucleoside transporter 3
別名Equilibrative nucleoside transporter 3; ENT3; HJCD; PHID; HCLAP; Solute carrier family 29 member 3; UNQ717/PRO1380; hENT3
应用说明
应用建议
应用推荐稀释比
IHC-P5 μg/mL for immunohistochemistry and 20 μg/mL for immunofluorescence
WB1 - 2 μg/mL
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
实际分子量50-70 kDa (70 kda might be protein with PTM)
属性
形式Liquid
纯化Affinity purification with immunogen.
缓冲液PBS and 0.02% Sodium azide.
抗菌剂0.02% Sodium azide
浓度1 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 353307 Rat SLC29A3

GeneID: 71279 Mouse SLC29A3

Swiss-port # Q80WK7 Rat Equilibrative nucleoside transporter 3

Swiss-port # Q99P65 Mouse Equilibrative nucleoside transporter 3

基因名称SLC29A3
全名solute carrier family 29 member 3
背景介绍This gene encodes a nucleoside transporter. The encoded protein plays a role in cellular uptake of nucleosides, nucleobases, and their related analogs. Mutations in this gene have been associated with H syndrome, which is characterized by cutaneous hyperpigmentation and hypertrichosis, hepatosplenomegaly, heart anomalies, and hypogonadism. A related disorder, PHID (pigmented hypertrichosis with insulin-dependent diabetes mellitus), has also been associated with mutations at this locus. Alternatively spliced transcript variants have been described.[provided by RefSeq, Mar 2010]
生物功能Mediates both influx and efflux of nucleosides across the membrane (equilibrative transporter). Mediates transport of adenine, adenosine and uridine, as well as several nucleoside analog drugs, such as anticancer and antiviral agents, including cladribine, cordycepin, tubercidin and AZT. Does not transport hypoxanthine.[provided by uniprot]
细胞定位Endosome, Lysosome, Membrane
预测分子量51.8 kDa
翻译后修饰Glycoprotein, Phosphoprotein
检测图片 (2)
  • ARG43456 anti-SLC29A3 / ENT3 antibody IHC-P image

    Immunofluorescence: Paraffin-embedded Rat colon muscle tissue stained with ARG43456 anti-SLC29A3 / ENT3 antibody at 20 µg/ml dilution.

  • ARG43456 anti-SLC29A3 / ENT3 antibody WB image

    Western blot: Mouse bladder tissue lysate stained with ARG43456 anti-SLC29A3 / ENT3 antibody at 1 or 2 µg/ml dilution and incubated at RT for 1 hour, in 5% NFDM/TBST.

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