anti-SLC47A2 / MATE2 antibody
CAT.NO. : ARG57586
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概述
产品描述 | Rabbit Polyclonal antibody recognizes SLC47A2 / MATE2 |
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反应物种 | Ms |
应用 | WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | SLC47A2 / MATE2 |
抗原物种 | Human |
抗原 | KLH-conjugated synthetic peptide corresponding to aa. 125-153 (N-terminus) of Human SLC47A2 / MATE2. |
偶联标记 | Un-conjugated |
別名 | Kidney-specific H; Multidrug and toxin extrusion protein 2; MATE2K; MATE-2; MATE2; MATE2-K; hMATE-2; Solute carrier family 47 member 2; MATE2-B |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
阳性对照 | Mouse kidney |
属性
形式 | Liquid |
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纯化 | Purification with Protein A and immunogen peptide. |
缓冲液 | PBS and 0.09% (W/V) Sodium azide. |
抗菌剂 | 0.09% (W/V) Sodium azide |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | Swiss-port # Q3V050 Mouse Multidrug and toxin extrusion protein 2 |
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基因名称 | SLC47A2 |
全名 | solute carrier family 47 (multidrug and toxin extrusion), member 2 |
背景介绍 | This gene encodes a protein belonging to a family of transporters involved in excretion of toxic electrolytes, both endogenous and exogenous, through urine and bile. This transporter family shares homology with the bacterial MATE (multidrug and toxin extrusion) protein family responsible for drug resistance. This gene is one of two members of the MATE transporter family located near each other on chromosome 17. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] |
生物功能 | Solute transporter for tetraethylammonium (TEA), 1-methyl-4-phenylpyridinium (MPP), cimetidine, N-methylnicotinamide, metformin, creatinine, guanidine, procainamide, topotecan, estrone sulfate, acyclovir, and ganciclovir. Responsible for the secretion of cationic drugs across the brush border membranes. [UniProt] |
细胞定位 | Cell membrane; Multi-pass membrane protein. Note=Localized at the brush border membranes of the proximal tubules |
预测分子量 | 65 kDa |
