anti-SLC4A7 antibody
CAT.NO. : ARG59872
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概述
| 产品描述 | Rabbit Polyclonal antibody recognizes SLC4A7 |
|---|---|
| 反应物种 | Ms |
| 预测物种 | Hu |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | SLC4A7 |
| 抗原物种 | Human |
| 抗原 | Recombinant fusion protein corresponding to aa. 240-400 of Human SLC4A7 (NP_003606.3). |
| 偶联标记 | Un-conjugated |
| 別名 | SBC2; NBC3; NBC2; NBCN1; Solute carrier family 4 member 7; Sodium bicarbonate cotransporter 2b; Bicarbonate transporter; 3; SLC4A6; Sodium bicarbonate cotransporter 3; Sodium bicarbonate cotransporter 2; Electroneutral Na/HCO |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | Mouse liver | ||||
| 实际分子量 | 160 kDa |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purified. |
| 缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 50% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 基因名称 | SLC4A7 |
|---|---|
| 全名 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 |
| 背景介绍 | This locus encodes a sodium bicarbonate cotransporter. The encoded transmembrane protein appears to transport sodium and bicarbonate ions in a 1:1 ratio, and is thus considered an electroneutral cotransporter. The encoded protein likely plays a critical role in regulation of intracellular pH involved in visual and auditory sensory transmission. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Apr 2012] |
| 生物功能 | Electroneutral sodium- and bicarbonate-dependent cotransporter with a Na(+):HCO3(-) 1:1 stoichiometry. Regulates intracellular pH and may play a role in bicarbonate salvage in secretory epithelia. May also have an associated sodium channel activity. [UniProt] |
| 细胞定位 | Basolateral cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein. Cell projection, stereocilium. Note=Also described at the apical cell membrane. Localizes to the stereocilia of cochlear outer hair cells and to the lateral membrane of cochlear inner hair cells (By similarity). [UniProt] |
| 预测分子量 | 136 kDa |
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