anti-SLC7A2 antibody
CAT.NO. : ARG40097
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概述
产品描述 | Rabbit Polyclonal antibody recognizes SLC7A2 |
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反应物种 | Hu, Ms, Rat |
应用 | IHC-P, WB |
宿主 | Rabbit |
克隆 | Polyclonal |
同位型 | IgG |
靶点名称 | SLC7A2 |
抗原物种 | Human |
抗原 | Synthetic peptide within aa. 500 to the C-terminus of Human SLC7A2 (NP_001008539.3). |
偶联标记 | Un-conjugated |
別名 | ATRC2; Solute carrier family 7 member 2; CAT-2; Cationic amino acid transporter 2; Low affinity cationic amino acid transporter 2; CAT2; HCAT2 |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||||
阳性对照 | Rat liver, Mouse brain and HepG2 | ||||||
实际分子量 | 80 kDa |
属性
形式 | Liquid |
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纯化 | Affinity purified. |
缓冲液 | PBS (pH 7.3), 0.02% Sodium azide and 50% Glycerol. |
抗菌剂 | 0.02% Sodium azide |
稳定剂 | 50% Glycerol |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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基因名称 | SLC7A2 |
全名 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 |
背景介绍 | The protein encoded by this gene is a cationic amino acid transporter and a member of the APC (amino acid-polyamine-organocation) family of transporters. The encoded membrane protein is responsible for the cellular uptake of arginine, lysine and ornithine. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] |
生物功能 | Functions as permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine); the affinity for its substrates differs between isoforms created by alternative splicing. Isoform 1 functions as permease that mediates the transport of the cationic amino acids (arginine, lysine and ornithine), and it has much higher affinity for arginine than isoform 2. Isoform 2 functions as low-affinity, high capacity permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine). May play a role in classical or alternative activation of macrophages via its role in arginine transport. [UniProt] |
细胞定位 | Cell membrane; Multi-pass membrane protein. [UniProt] |
预测分子量 | 72 kDa |
