anti-SM22 alpha / Transgelin antibody [TAGLN/247]
CAT.NO. : ARG40290
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概述
产品描述 | Mouse Monoclonal antibody [TAGLN/247] recognizes SM22 alpha / Transgelin |
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反应物种 | Hu |
应用 | IHC-P |
宿主 | Mouse |
克隆 | Monoclonal |
克隆号 | TAGLN/247 |
同位型 | IgG1, kappa |
靶点名称 | SM22 alpha / Transgelin |
抗原物种 | Human |
抗原 | Recombinant full-length Human SM22 alpha / Transgelin. |
偶联标记 | Un-conjugated |
別名 | SM22-alpha; 22 kDa actin-binding protein; Smooth muscle protein 22-alpha; Protein WS3-10; Transgelin; WS3-10; TAGLN1; SMCC; SM22 |
应用说明
应用建议 |
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应用说明 | IHC-P: Antigen Retrieval: Boil tissue section in 10 mM Tris with 1 mM EDTA (pH 9.0), for 10-20 min followed by cooling at RT for 20 min. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化 | Purification with Protein G. |
缓冲液 | PBS, 0.05% Sodium azide and 0.1 mg/ml BSA. |
抗菌剂 | 0.05% Sodium azide |
稳定剂 | 0.1 mg/ml BSA |
浓度 | 0.2 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | |
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基因名称 | TAGLN |
全名 | transgelin |
背景介绍 | The protein encoded by this gene is a transformation and shape-change sensitive actin cross-linking/gelling protein found in fibroblasts and smooth muscle. Its expression is down-regulated in many cell lines, and this down-regulation may be an early and sensitive marker for the onset of transformation. A functional role of this protein is unclear. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] |
生物功能 | Actin cross-linking/gelling protein (By similarity). Involved in calcium interactions and contractile properties of the cell that may contribute to replicative senescence. [UniProt] |
细胞定位 | Cytoplasm. [UniProt] |
研究领域 | Cell Biology and Cellular Response antibody; Controls and Markers antibody; Signaling Transduction antibody; Smooth Muscle Marker antibody |
预测分子量 | 23 kDa |
检测图片 (2)
ARG40290 anti-SM22 alpha / Transgelin antibody [TAGLN/247] IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded Human colon carcinoma stained with ARG40290 anti-SM22 alpha / Transgelin antibody [TAGLN/247].
ARG40290 anti-SM22 alpha / Transgelin antibody [TAGLN/247] IHC-P image
Immunohistochemistry: Formalin-fixed and paraffin-embedded Human colon carcinoma stained with ARG40290 anti-SM22 alpha / Transgelin antibody [TAGLN/247].
