anti-SMO / Smoothened Homolog antibody
Key features and details
- 产品描述:
- 反应物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
- 抗原:
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Brand:
CAT.NO. : ARG22356
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes SMO / Smoothened Homolog |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | SMO / Smoothened Homolog |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide of Human SMO / Smoothened Homolog. |
| 偶联标记 | Un-conjugated |
| 別名 | Gx; SMO; Protein Gx; Smoothened homolog; FZD11; SMOH |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. | ||||
| 阳性对照 | Human brain. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Ammonium sulfate precipitation. |
| 缓冲液 | PBS and 0.08% Sodium azide. |
| 抗菌剂 | 0.08% Sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | SMO |
| 全名 | smoothened, frizzled class receptor |
| 背景介绍 | The protein encoded by this gene is a G protein-coupled receptor that interacts with the patched protein, a receptor for hedgehog proteins. The encoded protein tranduces signals to other proteins after activation by a hedgehog protein/patched protein complex. [provided by RefSeq, Jul 2010] |
| 生物功能 | G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO). Required for the accumulation of KIF7 and GLI3 in the cilia. [UniProt] |
| 预测分子量 | 86 kDa |
检测图片 (1)
ARG22356 anti-SMO / Smoothened Homolog antibody WB image
Western blot: 15 µg of Human brain lysate stained with ARG22356 anti-SMO / Smoothened Homolog antibody at 1) 10 µg/ml, and 2) 5 µg/ml dilution.
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