anti-SOAT1 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes SOAT1
  • 反应物种: Hu, Ms, Rat, Pig
  • 应用: ICC/IF, IHC-Fr, IHC-P, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: SOAT1
  • 抗原物种: Human
  • 抗原: Synthetic peptide around the N-terminus of Human SOAT 1.
  • Brand:
CAT.NO. : ARG56476
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes SOAT1
反应物种Hu, Ms, Rat, Pig
应用ICC/IF, IHC-Fr, IHC-P, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称SOAT1
抗原物种Human
抗原Synthetic peptide around the N-terminus of Human SOAT 1.
偶联标记Un-conjugated
別名STAT; ACACT; Cholesterol acyltransferase 1; Sterol O-acyltransferase 1; ACAT-1; ACAT1; ACAT; SOAT; Acyl-coenzyme A:cholesterol acyltransferase 1; EC 2.3.1.26
应用说明
应用建议
应用推荐稀释比
ICC/IF1:50 - 1:200
IHC-Fr1:50 - 1:200
IHC-P1:200
WB1:200
应用说明IHC-P: Antigen Retrieval: Heat mediation was performed in Citrate buffer (pH 6.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Affinity purification with immunogen.
缓冲液TBS (pH 7.4), 0.02% Sodium azide, 50% Glycerol and 0.1% BSA.
抗菌剂0.02% Sodium azide
稳定剂50% Glycerol and 0.1% BSA
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 20652 Mouse SOAT1

GeneID: 6646 Human SOAT1

GeneID: 81782 Rat SOAT1

基因名称SOAT1
全名sterol O-acyltransferase 1
背景介绍The protein encoded by this gene belongs to the acyltransferase family. It is located in the endoplasmic reticulum, and catalyzes the formation of fatty acid-cholesterol esters. This gene has been implicated in the formation of beta-amyloid and atherosclerotic plaques by controlling the equilibrium between free cholesterol and cytoplasmic cholesteryl esters. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2011]
生物功能Catalyzes the formation of fatty acid-cholesterol esters, which are less soluble in membranes than cholesterol. Plays a role in lipoprotein assembly and dietary cholesterol absorption. In addition to its acyltransferase activity, it may act as a ligase. [UniProt]
产品亮点Related products:
Anti-Rabbit IgG secondary antibodies;
Related news:
Cholesterol, the weakness of anaplastic large cell lymphoma (ALCL)
预测分子量65 kDa
检测图片 (4)
  • ARG56476 anti-SOAT1 antibody IHC-P image

    Immunohistochemistry: Formalin-fixed and paraffin-embedded Human adrenal tissue. Antigen Retrieval: Heat mediation was performed in Citrate buffer (pH 6.0). Tissue section was stained with ARG56476 anti-SOAT1 antibody at 1:200 dilution.

  • ARG56476 anti-SOAT1 antibody WB image

    Western blot: 30 µg of Rat liver and HepG2 cell lysates stained with ARG56476 anti-SOAT1 antibody.

  • ARG56476 anti-SOAT1 antibody ICC/IF image

    Immunofluorescence: Paraformaldehyde fixed A549 cells stained with ARG56476 anti-SOAT1 antibody (green) at 1:200 dilution.

  • ARG56476 anti-SOAT1 antibody ICC/IF image

    Immunofluorescence: Paraformaldehyde fixed Mouse Macrophages stained with ARG56476 anti-SOAT1 antibody (red).

参考文献

Sterol O-acyltransferase 2 chaperoned by apolipoprotein J facilitates hepatic lipid accumulation following viral and nutrient stresses.

WB / Human

Hung-Yu Sun et al.
Commun Biol.,  (2021)

publication_link

 

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