anti-Sorbitol Dehydrogenase antibody [10F4]

Key features and details

  • 产品描述: Mouse Monoclonal antibody [10F4] recognizes Sorbitol Dehydrogenase
  • 反应物种: Hu
  • 应用: WB
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 克隆号: 10F4
  • 同位型: IgG1, kappa
  • 靶点名称: Sorbitol Dehydrogenase
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG57128
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Product Details
概述
产品描述Mouse Monoclonal antibody [10F4] recognizes Sorbitol Dehydrogenase
反应物种Hu
应用WB
宿主Mouse
克隆Monoclonal
克隆号10F4
同位型IgG1, kappa
靶点名称Sorbitol Dehydrogenase
抗原物种Human
抗原Recombinant fragment around aa. 1-357 of Human Sorbitol Dehydrogenase
偶联标记Un-conjugated
別名SORD1; L-iditol 2-dehydrogenase; Sorbitol dehydrogenase; HEL-S-95n; EC 1.1.1.14
应用说明
应用建议
应用推荐稀释比
WB1:1000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purification with Protein A.
缓冲液PBS (pH 7.4), 0.02% Sodium azide and 10% Glycerol.
抗菌剂0.02% Sodium azide
稳定剂10% Glycerol
浓度1 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 6652 Human SORD

Swiss-port # Q00796 Human Sorbitol dehydrogenase

基因名称SORD
全名sorbitol dehydrogenase
背景介绍Sorbitol dehydrogenase (SORD; EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1; MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor.[supplied by OMIM, Jul 2010]
生物功能Converts sorbitol to fructose. Part of the polyol pathway that plays an important role in sperm physiology. May play a role in the sperm motility by providing an energetic source for sperm. [UniProt]
预测分子量38 kDa
检测图片 (2)
  • ARG57128 anti-Sorbitol Dehydrogenase antibody [10F4] WB image

    Western blot: 40 µg of Jurkat cell lysate stained with ARG57128 anti-Sorbitol Dehydrogenase antibody [10F4] at 1:1000.

  • ARG57128 anti-Sorbitol Dehydrogenase antibody [10F4] WB image

    Western blot: 1) 20 ng of SORD recombinant protein, and 2) 40 µg of HeLa cell lysate stained with ARG57128 anti-Sorbitol Dehydrogenase antibody [10F4] at 1:1000.

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