anti-Sorbitol Dehydrogenase antibody

Key features and details

  • 产品描述: Goat Polyclonal antibody recognizes Sorbitol Dehydrogenase
  • 反应物种: Ms
  • 预测物种: Hu, Rat, Dog
  • 应用: IHC-P, WB
  • 宿主: Goat
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: Sorbitol Dehydrogenase
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG63681
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Product Details
概述
产品描述Goat Polyclonal antibody recognizes Sorbitol Dehydrogenase
反应物种Ms
预测物种Hu, Rat, Dog
应用IHC-P, WB
宿主Goat
克隆Polyclonal
同位型IgG
靶点名称Sorbitol Dehydrogenase
抗原物种Human
抗原KIMLKCDPSDQNP
偶联标记Un-conjugated
別名SORD1; L-iditol 2-dehydrogenase; Sorbitol dehydrogenase; HEL-S-95n; EC 1.1.1.14
应用说明
应用建议
应用推荐稀释比
IHC-PAssay - dependent
WB0.1 - 0.3 µg/ml
应用说明WB: Recommend incubate at RT for 1h.
IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
缓冲液Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
抗菌剂0.02% Sodium azide
稳定剂0.5% BSA
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 20322 Mouse SORD

Swiss-port # Q64442 Mouse Sorbitol dehydrogenase

背景介绍Sorbitol dehydrogenase (SORD; EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1; MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor.[supplied by OMIM, Jul 2010]
研究领域Metabolism antibody; Signaling Transduction antibody
预测分子量38 kDa
检测图片 (2)
  • ARG63681 anti-Sorbitol Dehydrogenase antibody WB image

    Western Blot: Mouse Kidney lysate (35 µg protein in RIPA buffer) stained with ARG63681 anti-Sorbitol Dehydrogenase antibody at 0.1 µg/ml dilution.

  • ARG63681 anti-Sorbitol Dehydrogenase antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human prostate tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG63681 anti-Sorbitol Dehydrogenase antibody at 5 µg/ml dilution followed by AP-staining.

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