anti-SOX10 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes SOX10
  • 反应物种: Rat
  • 应用: IHC-P, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: SOX10
  • 抗原物种: Human
  • 抗原: An 18 amino acid peptide near the N-terminus of Human SOX10.
  • Brand:
CAT.NO. : ARG41957
US$ Please choose
US$ Please choose
Size:
Trail, Bulk size or Custom requests Please contact us
*产品价格可能会有所调整,请以品牌方官网实时更新的价格为准,以确保准确性。
Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes SOX10
反应物种Rat
应用IHC-P, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称SOX10
抗原物种Human
抗原An 18 amino acid peptide near the N-terminus of Human SOX10.
偶联标记Un-conjugated
別名WS4C; PCWH; DOM; Transcription factor SOX-10; WS2E; WS4
应用说明
应用建议
应用推荐稀释比
IHC-P5 - 20 µg/ml
WB1 - 2 µg/ml
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照Rat heart
实际分子量~ 54 kDa
属性
形式Liquid
纯化Affinity purification with immunogen.
缓冲液PBS and 0.02% Sodium azide.
抗菌剂0.02% Sodium azide
浓度1 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 29361 Rat SOX10

Swiss-port # O55170 Rat Transcription factor SOX-10

基因名称SOX10
全名SRY (sex determining region Y)-box 10
背景介绍SOX10 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease. [provided by RefSeq, Jul 2008]
生物功能SOX10 is a transcription factor that plays a central role in developing and mature glia. Specifically activates expression of myelin genes, during oligodendrocyte (OL) maturation, such as DUSP15 and MYRF, thereby playing a central role in oligodendrocyte maturation and CNS myelination. Once induced, MYRF cooperates with SOX10 to implement the myelination program. Transcriptional activator of MITF, acting synergistically with PAX3 (PubMed:21965087). [UniProt]
细胞定位Cytoplasm. Nucleus. Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side. [UniProt]
预测分子量50 kDa
检测图片 (3)
  • ARG41957 anti-SOX10 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Rat heart tissue stained with ARG41957 anti-SOX10 antibody at 5 µg/ml dilution.

  • ARG41957 anti-SOX10 antibody WB image

    Western blot: Rat heart lysates stained with ARG41957 anti-SOX10 antibody at 1 and 2 µg/ml dilution.

  • ARG41957 anti-SOX10 antibody IHC image

    Immunohistochemistry: Rat heart tissue stained with ARG41957 anti-SOX10 antibody at 20 µg/ml dilution.

New Products
Get in touch with AREX
Name:*
Tel/Phone:*
Company:*
Email:*
Inquiry:
Captcha*
Submitting your email information means that you are willing to receive email information from AREX regarding technology, applications, products, and events. By clicking on the 'unsubscribe' button in the email or by contacting info@arexbio.com You can unsubscribe at any time by sending an email. Regarding your data usage information, please refer to our privacy policy.
© AREX 2024. All Rights Reserved. | 浙ICP备2024113709号-3 Sitemap