anti-SPHK1 antibody
Key features and details
- 产品描述:
- 反应物种:
- 预测物种:
- 应用:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
- 抗原物种:
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Brand:
CAT.NO. : ARG56527
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Product Details
概述
| 产品描述 | Rabbit Polyclonal antibody recognizes SPHK1 |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Ms, Pig, Rb, frg |
| 应用 | ICC/IF, WB |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | SPHK1 |
| 抗原物种 | Human |
| 抗原 | Synthetic peptide around an internal region of Human SPHK1. |
| 偶联标记 | Un-conjugated |
| 別名 | SK 1; SPK 1; EC 2.7.1.91; SPHK; Sphingosine kinase 1 |
应用说明
| 应用建议 |
| ||||||
|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | SPHK1 |
| 全名 | sphingosine kinase 1 |
| 背景介绍 | The protein encoded by this gene catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein-coupled receptors. This protein, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011] |
| 生物功能 | Catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra- and extracellular functions. Also acts on D-erythro-sphingosine and to a lesser extent sphinganine, but not other lipids, such as D,L-threo-dihydrosphingosine, N,N-dimethylsphingosine, diacylglycerol, ceramide, or phosphatidylinositol. [UniProt] |
| 预测分子量 | 43 kDa |
检测图片 (1)
ARG56527 anti-SPHK1 antibody WB image
Western blot: 1) Precision Plus Protein Standard, 2) 10 µg of SPHK 1 transfected cell lysates, 3) 20 µg of SPHK 1 transfected cell lysates, 4) 25 µg of Mouse heart homogenate, and 5) 50 µg of Mouse heart homogenate stained with ARG56527 anti-SPHK1 antibody.
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