anti-Spindly / CCDC99 antibody
CAT.NO. : ARG44942
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概述
| 产品描述 | Mouse Monoclonal antibody recognizes Spindly / CCDC99 |
|---|---|
| 反应物种 | Hu |
| 应用 | WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 同位型 | IgG2a |
| 靶点名称 | Spindly / CCDC99 |
| 抗原物种 | Human |
| 偶联标记 | Un-conjugated |
| 別名 | SPDL1; Spindle Apparatus Coiled-Coil Protein 1; HSpindly; CCDC99; Coiled-Coil Domain-Containing Protein 99; Rhabdomyosarcoma Antigen MU-RMS-40.4A; Arsenite-Related Gene 1 Protein; Protein Spindly; FLJ20364; Spindle Apparatus Coiled-Coil Domain-Containing Protein 1; Rrhabdomyosarcoma Antigen Protein MU-RMS-40.4A; Coiled-Coil Domain Containing 99; Spindly Homolog (Drosophila) |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein A purification |
| 缓冲液 | PBS with 0.09% sodium azide |
| 抗菌剂 | 0.09% sodium azide |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | SPDL1 |
| 全名 | Spindle Apparatus Coiled-Coil Protein 1 |
| 背景介绍 | This gene encodes a coiled-coil domain-containing protein that functions in mitotic spindle formation and chromosome segregation. The encoded protein plays a role in coordinating microtubule attachment by promoting recruitment of dynein proteins, and in mitotic checkpoint signaling. [provided by RefSeq, Jul 2016] |
| 生物功能 | Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track). [UniProt] |
| 细胞定位 | Centromere, Chromosome, Cytoplasm, Cytoskeleton, Kinetochore, Nucleus. [UniProt] |
| 翻译后修饰 | Acetylation, Phosphoprotein, Ubl conjugation. [UniProt] |
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