anti-SRD5A1 / 5-alpha reductase 1 antibody
CAT.NO. : ARG65801
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概述
| 产品描述 | Rabbit Polyclonal antibody recognizes SRD5A1 / 5-alpha reductase 1 |
|---|---|
| 反应物种 | Hu, Rat |
| 应用 | WB |
| 特异性 | Recognizes endogenous levels of SRD5A1 protein. |
| 宿主 | Rabbit |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | SRD5A1 / 5-alpha reductase 1 |
| 抗原物种 | Human |
| 抗原 | KLH-conjugated synthetic peptide around the C-terminus of Human SRD5A1. |
| 偶联标记 | Un-conjugated |
| 別名 | 3-oxo-5-alpha-steroid 4-dehydrogenase 1; S5AR 1; Steroid 5-alpha-reductase 1; EC 1.3.1.22; SR type 1 |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Affinity purification with immunogen. |
| 缓冲液 | Liquid (pH 7.3), 0.42% Potassium phosphate, 0.87% NaCl, 0.01% Sodium azide and 30% Glycerol. |
| 抗菌剂 | 0.01% Sodium azide |
| 稳定剂 | 30% Glycerol |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # P18405 Human 3-oxo-5-alpha-steroid 4-dehydrogenase 1 Swiss-port # P24008 Rat 3-oxo-5-alpha-steroid 4-dehydrogenase 1 |
|---|---|
| 基因名称 | SRD5A1 |
| 全名 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) |
| 背景介绍 | Steroid 5-alpha-reductase (EC 1.3.99.5) catalyzes the conversion of testosterone into the more potent androgen, dihydrotestosterone (DHT). Also see SRD5A2 (MIM 607306).[supplied by OMIM, Mar 2008] |
| 生物功能 | Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology. [UniProt] |
| 预测分子量 | 29 kDa |
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