anti-SRGAP2 antibody

Key features and details

  • 产品描述: Goat Polyclonal antibody recognizes SRGAP2
  • 反应物种: Hu, Rat
  • 预测物种: Ms, Cow, Dog
  • 应用: ICC/IF, WB
  • 特异性: This antibody is expected to recognize isoform a (NP_056141.2).
  • 宿主: Goat
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: SRGAP2
  • Brand:
CAT.NO. : ARG65308
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Product Details
概述
产品描述Goat Polyclonal antibody recognizes SRGAP2
反应物种Hu, Rat
预测物种Ms, Cow, Dog
应用ICC/IF, WB
特异性This antibody is expected to recognize isoform a (NP_056141.2).
宿主Goat
克隆Polyclonal
同位型IgG
靶点名称SRGAP2
抗原物种Human
抗原C-KQEDRQTPRSPDST
偶联标记Un-conjugated
別名FNBP2; SRGAP3; srGAP2; ARHGAP34; SLIT-ROBO Rho GTPase-activating protein 2; Formin-binding protein 2; Rho GTPase-activating protein 34; SRGAP2A
应用说明
应用建议
应用推荐稀释比
ICC/IFAssay - dependent
WB0.1 - 0.3 µg/ml
应用说明WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
缓冲液Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
抗菌剂0.02% Sodium azide
稳定剂0.5% BSA
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 23380 Human SRGAP2

GeneID: 360840 Rat SRGAP2

Swiss-port # D4A208 Rat SLIT-ROBO Rho GTPase-activating protein 2

Swiss-port # O75044 Human SLIT-ROBO Rho GTPase-activating protein 2

背景介绍This locus encodes a member of the SLIT-ROBO Rho GTPase activating protein family. The encoded protein stimulates GTPase activity of Rac1, and plays a role in cortical neuron development. This locus has several paralogs on human chromosome 1 resulting from segmental duplication. While this locus itself is conserved among various species, the paralogs are found only in the genus Homo, and not in the genomes of non-human great apes. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Jul 2014]
研究领域Neuroscience antibody; Signaling Transduction antibody
预测分子量121 kDa
翻译后修饰Methylation at Arg-927 is required for the stimulation of cell migration, dimerization and localization at the plasma membrane protrusions.
检测图片 (1)
  • ARG65308 anti-SRGAP2 antibody WB image

    Western blot: 35 µg of Rat cortical neuron lysate stained with ARG65308 anti-SRGAP2 antibody at 0.1 µg/ml dilution and incubated for 1 hour.

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