anti-Staphylococcus Enterotoxin B antibody [SEB]
CAT.NO. : ARG10080
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概述
产品描述 | Mouse Monoclonal antibody [SEB] recognizes Staphylococcus Enterotoxin B |
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反应物种 | S. aureus |
应用 | ELISA |
宿主 | Mouse |
克隆 | Monoclonal |
克隆号 | SEB |
同位型 | IgG1, kappa |
靶点名称 | Staphylococcus Enterotoxin B |
抗原物种 | Bacteria |
抗原 | SEB purified from Staphylococcus aureus |
偶联标记 | Un-conjugated |
应用说明
应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
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属性
形式 | Liquid |
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纯化 | Protein G affinity purified |
缓冲液 | 0.01M PBS (pH 7.2) |
浓度 | 1 mg/ml |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
背景介绍 | Staphylococcal enterotoxin B (SEB) is an enterotoxin secreted by Staphylococcus aureus.The bacterium thrives on meet, baking and dairy products and also colonizes in host nasal passageway.Ingestion of SEB contaminated food is the common cause of “food poisoning”, manifested by flu-like symptoms, vomiting, diarrhea and intestinal cramps.In severe cases, SEB can cause respiratory failure and systemic toxic shock.These symptoms are the results of increased membrane permeability and abnormal activation of T-lymphocytes by SEB. SEB acts as a superantigen by binding directly to major histocompatibility complex class II (MHCII) on antigen presenting cells, thus, causing massive CD4 and CD8 T-cells activation and cytokine production.If unchecked, the process can result in systemic organ failure and death. |
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研究领域 | Microbiology and Infectious Disease antibody |
