anti-Staphylococcus Enterotoxin B antibody [SEB]

Key features and details

  • 产品描述: Mouse Monoclonal antibody [SEB] recognizes Staphylococcus Enterotoxin B
  • 反应物种: S. aureus
  • 应用: ELISA
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 克隆号: SEB
  • 同位型: IgG1, kappa
  • 靶点名称: Staphylococcus Enterotoxin B
  • 抗原物种: Bacteria
  • Brand:
CAT.NO. : ARG10080
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Product Details
概述
产品描述Mouse Monoclonal antibody [SEB] recognizes Staphylococcus Enterotoxin B
反应物种S. aureus
应用ELISA
宿主Mouse
克隆Monoclonal
克隆号SEB
同位型IgG1, kappa
靶点名称Staphylococcus Enterotoxin B
抗原物种Bacteria
抗原SEB purified from Staphylococcus aureus
偶联标记Un-conjugated
应用说明
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Protein G affinity purified
缓冲液0.01M PBS (pH 7.2)
浓度1 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
背景介绍Staphylococcal enterotoxin B (SEB) is an enterotoxin secreted by Staphylococcus aureus.The bacterium thrives on meet, baking and dairy products and also colonizes in host nasal passageway.Ingestion of SEB contaminated food is the common cause of “food poisoning”, manifested by flu-like symptoms, vomiting, diarrhea and intestinal cramps.In severe cases, SEB can cause respiratory failure and systemic toxic shock.These symptoms are the results of increased membrane permeability and abnormal activation of T-lymphocytes by SEB. SEB acts as a superantigen by binding directly to major histocompatibility complex class II (MHCII) on antigen presenting cells, thus, causing massive CD4 and CD8 T-cells activation and cytokine production.If unchecked, the process can result in systemic organ failure and death.
研究领域Microbiology and Infectious Disease antibody
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