anti-STAT4 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes STAT4
  • 反应物种: Hu, Rat
  • 预测物种: Chk
  • 应用: WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: STAT4
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG41768
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes STAT4
反应物种Hu, Rat
预测物种Chk
应用WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称STAT4
抗原物种Human
抗原Synthetic peptide corresponding to aa. 1-17 of Human STAT4. (MSQWNQVQQLEIKFLEQ)
偶联标记Un-conjugated
別名SLEB11; Signal transducer and activator of transcription 4
应用说明
应用建议
应用推荐稀释比
WB1:500 - 1:2000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
实际分子量~ 86 kDa
属性
形式Liquid
纯化Affinity purification with immunogen.
缓冲液0.2% Na2HPO4, 0.9% NaCl, 0.05% Thimerosal, 0.05% Sodium azide and 5% BSA.
抗菌剂0.05% Thimerosal and 0.05% Sodium azide
稳定剂5% BSA
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 6775 Human STAT4

Swiss-port # Q14765 Human Signal transducer and activator of transcription 4

基因名称STAT4
全名signal transducer and activator of transcription 4
背景介绍The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011]
生物功能Carries out a dual function: signal transduction and activation of transcription. Involved in IL12 signaling. [UniProt]
细胞定位Cytoplasm. Nucleus. Note=Translocated into the nucleus in response to phosphorylation. [UniProt]
预测分子量86 kDa
翻译后修饰Tyrosine phosphorylated. Serine phosphorylation is also required for maximal transcriptional activity (By similarity). [UniProt]
检测图片 (1)
  • ARG41768 anti-STAT4 antibody WB image

    Western blot: Rat testis, U87 and HeLa cell lysates stained with ARG41768 anti-STAT4 antibody.

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