anti-STAT6 phospho (Thr645) antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes STAT6 phospho (Thr645)
  • 反应物种: Hu
  • 应用: IHC-P, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: STAT6
  • 抗原物种: Human
  • 抗原: Peptide sequence around phosphorylation site of threonine 645 (P-A-T(p)-I-K) derived from Human STAT6.
  • Brand:
CAT.NO. : ARG51555
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes STAT6 phospho (Thr645)
反应物种Hu
应用IHC-P, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称STAT6
抗原物种Human
抗原Peptide sequence around phosphorylation site of threonine 645 (P-A-T(p)-I-K) derived from Human STAT6.
偶联标记Un-conjugated
別名D12S1644; STAT6B; STAT6C; Signal transducer and activator of transcription 6; IL-4-STAT; IL-4 Stat
应用说明
应用建议
应用推荐稀释比
IHC-P1:50 - 1:100
WB1:500 - 1:1000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Antibodies were produced by immunizing rabbits with KLH-conjugated synthetic phosphopeptide. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. In addition, non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
缓冲液PBS (without Mg2+ and Ca2+, pH 7.4), 150mM NaCl, 0.02% Sodium azide and 50% Glycerol.
抗菌剂0.02% Sodium azide
稳定剂50% Glycerol
浓度1 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 6778 Human STAT6

Swiss-port # P42226 Human Signal transducer and activator of transcription 6

基因名称STAT6
全名signal transducer and activator of transcription 6, interleukin-4 induced
背景介绍Carries out a dual function: signal transduction and activation of transcription. Involved in interleukin-4 signalling.
生物功能Carries out a dual function: signal transduction and activation of transcription. Involved in IL4/interleukin-4- and IL3/interleukin-3-mediated signaling. [UniProt]
研究领域Gene Regulation antibody; Signaling Transduction antibody
预测分子量94 kDa
翻译后修饰Tyrosine phosphorylated following stimulation by IL4/interleukin-4 and IL3/interleukin-3 (By similarity). Dephosphorylation on tyrosine residues by PTPN2 negatively regulates the IL4/interleukin-4 mediated signaling.
检测图片 (2)
  • ARG51555 anti-STAT6 phospho (Thr645) antibody WB image

    Western blot: Extracts from HeLa cells, treated with IL-4 or calf intestinal phosphatase (CIP), stained with ARG51555 anti-STAT6 phospho (Thr645) antibody.

  • ARG51555 anti-STAT6 phospho (Thr645) antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human breast carcinoma tissue stained with ARG51555 anti-STAT6 phospho (Thr645) antibody (left) or the same antibody preincubated with blocking peptide (right).

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