anti-STMN2 / SCG10 antibody

Key features and details

  • 产品描述: Goat Polyclonal antibody recognizes STMN2 / SCG10
  • 反应物种: Ms
  • 预测物种: Hu, Rat, Cow, Dog
  • 应用: IHC-P, WB
  • 宿主: Goat
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: STMN2 / SCG10
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG63628
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Product Details
概述
产品描述Goat Polyclonal antibody recognizes STMN2 / SCG10
反应物种Ms
预测物种Hu, Rat, Cow, Dog
应用IHC-P, WB
宿主Goat
克隆Polyclonal
同位型IgG
靶点名称STMN2 / SCG10
抗原物种Human
抗原AKTAMAYKEK-C
偶联标记Un-conjugated
別名Protein SCG10; SCG10; SCGN10; Stathmin-2; Superior cervical ganglion-10 protein
应用说明
应用建议
应用推荐稀释比
IHC-PAssay - dependent
WB0.3 - 1 µg/ml
应用说明WB: Recommend incubate at RT for 1h.
IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
缓冲液Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
抗菌剂0.02% Sodium azide
稳定剂0.5% BSA
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 20257 Mouse STMN2

Swiss-port # P55821 Mouse Stathmin-2

背景介绍This gene encodes a member of the stathmin family of phosphoproteins. Stathmin proteins function in microtubule dynamics and signal transduction. The encoded protein plays a regulatory role in neuronal growth and is also thought to be involved in osteogenesis. Reductions in the expression of this gene have been associated with Down's syndrome and Alzheimer's disease. Alternatively spliced transcript variants have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 6. [provided by RefSeq, Nov 2010]
研究领域Neuroscience antibody
预测分子量21 kDa
翻译后修饰Sumoylated.
Phosphorylated mostly by MAPK8, but also by MAPK9 and MAPK10 in the developing brain cortex.
N-terminal palmitoylation promotes specific anchoring to the cytosolic leaflet of Golgi membranes and subsequent vesicular trafficking along dendrites and axons. Neuronal Stathmins are substrates for palmitoyltransferases ZDHHC3, ZDHHC7 and ZDHHC15.
检测图片 (3)
  • ARG63628 anti-STMN2 / SCG10 antibody WB image

    Western Blot: Human Brain lysate (RIPA buffer, 35 µg total protein per lane) stained with ARG63628 anti-STMN2 / SCG10 antibody at 1 µg/ml dilution.

  • ARG63628 anti-STMN2 / SCG10 antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human small intestine tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG63628 anti-STMN2 / SCG10 antibody at 5 µg/ml dilution followed by AP-staining.

  • ARG63628 anti-STMN2 / SCG10 antibody WB image

    Western blot: 35 µg of Mouse foetal brain lysate (in RIPA buffer) stained with ARG63628 anti-STMN2 / SCG10 antibody at 0.5 µg/ml dilution and incubated at RT for 1 hour.

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