anti-STRO1 antibody [STRO-1] (PE)
![anti-STRO1 antibody [STRO-1] (PE)](/upload/image/products/ARG54297_FACS_1_210_205.jpg)
![anti-STRO1 antibody [STRO-1] (PE)](/upload/image/products/ARG54297_FACS_1.jpg)
Key features and details
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CAT.NO. : ARG54297
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Product Details
概述
| 产品描述 | PE-conjugated Mouse Monoclonal antibody [STRO-1] recognizes STRO1 |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS |
| 特异性 | The clone STRO-1 recognizes the cell surface antigen STRO-1 expressed by bone marrow mesenchymal stromal cells and nucleated erythroid precursors, but not by committed hematopoietic progenitors. |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | STRO-1 |
| 同位型 | IgM |
| 靶点名称 | STRO1 |
| 抗原物种 | Human |
| 抗原 | Human CD34 positive bone marrow cells |
| 偶联标记 | PE |
应用说明
| 应用建议 |
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|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化说明 | The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography. |
| 缓冲液 | TBS, 15 mM Sodium azide and 0.2% (w/v) high-grade protease free BSA |
| 抗菌剂 | 15 mM Sodium azide |
| 稳定剂 | 0.2% (w/v) high-grade protease free BSA |
| 浓度 | 0.1 mg/ml |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 背景介绍 | STRO-1 is a cell surface antigen expressed by stromal elements in human bone marrow, identified by monoclonal antibody STRO-1. Approximately 10% of mononuclear cells, greater than 95% of which are nucleated erythroid precursors, are STRO-1 positive, whereas the CFU-GM (colony-forming unit granulocyte-macrophage), BFU-E (erythroid burst) and CFU-Mix (mixed colonies) committed progenitor cells are negative. CFU-F (fibroblast colony-forming cells) are present exclusively in the STRO-1 positive population. When plated under long-term bone marrow culture conditions, STRO-1 positive cells generate adherent cell layers containing multiple stromal cell types, including adipocytes, smooth muscle cells, osteoblasts, chondrocytes, and fibroblastic elements. In combination with glycophorin A, STRO-1 is a useful marker for identification of mesenchymal stem cells. STRO-1 and CD117 are markers for osteosarcoma cells. |
|---|---|
| 研究领域 | Controls and Markers antibody |
检测图片 (1)
ARG54297 anti-STRO1 antibody [STRO-1] (PE) FACS image
Flow Cytometry: Human peripheral blood stained with ARG54297 anti-STRO1 antibody [STRO-1] (PE) and anti-CD45 antibody (Pacific Blue).
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