anti-STUB1 / CHIP antibody

Key features and details

  • 产品描述: Goat Polyclonal antibody recognizes STUB1 / CHIP
  • 反应物种: Hu
  • 预测物种: Ms, Rat, Cow, Dog
  • 应用: IHC-P, WB
  • 宿主: Goat
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: STUB1 / CHIP
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG63584
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Product Details
概述
产品描述Goat Polyclonal antibody recognizes STUB1 / CHIP
反应物种Hu
预测物种Ms, Rat, Cow, Dog
应用IHC-P, WB
宿主Goat
克隆Polyclonal
同位型IgG
靶点名称STUB1 / CHIP
抗原物种Human
抗原C-DAFISENGWVEDY
偶联标记Un-conjugated
別名NY-CO-7; Antigen NY-CO-7; UBOX1; EC 6.3.2.-; E3 ubiquitin-protein ligase CHIP; SDCCAG7; CHIP; STIP1 homology and U box-containing protein 1; HSPABP2; SCAR16; Carboxy terminus of Hsp70-interacting protein; CLL-associated antigen KW-8
应用说明
应用建议
应用推荐稀释比
IHC-PAssay - dependent
WB0.3 - 1 µg/ml
应用说明WB: Recommend incubate at RT for 1h.
IHC-P: Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
缓冲液Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
抗菌剂0.02% Sodium azide
稳定剂0.5% BSA
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 10273 Human STUB1

Swiss-port # Q9UNE7 Human E3 ubiquitin-protein ligase CHIP

背景介绍STUB1, or CHIP, is a ubiquitin ligase/cochaperone that participates in protein quality control by targeting a broad range of chaperone protein substrates for degradation (Min et al., 2008 [PubMed 18411298]).[supplied by OMIM, Jul 2009]
研究领域Gene Regulation antibody; Signaling Transduction antibody
预测分子量35 kDa
翻译后修饰Monoubiquitinated at Lys-2 following cell stress by UBE2W, promoting the interaction with ATXN3 (By similarity). Auto-ubiquitinated; mediated by UBE2D1 and UBE2D2.
检测图片 (2)
  • ARG63584 anti-STUB1 / CHIP antibody WB image

    Western Blot: Human Muscle lysate (RIPA buffer, 35 µg total protein per lane) stained with ARG63584 anti-STUB1 / CHIP antibody at 0.3 µg/ml dilution.

  • ARG63584 anti-STUB1 / CHIP antibody IHC-P image

    Immunohistochemistry: Paraffin-embedded Human small intestine tissue. Antigen Retrieval: Steam tissue section in Citrate buffer (pH 6.0). The tissue section was stained with ARG63584 anti-STUB1 / CHIP antibody at 2.5 µg/ml dilution followed by AP-staining.

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