anti-SULT2B1 antibody
CAT.NO. : ARG44746
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概述
产品描述 | Mouse Monoclonal antibody recognizes SULT2B1 |
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反应物种 | Hu |
应用 | IHC-P, IP, WB |
宿主 | Mouse |
克隆 | Monoclonal |
同位型 | IgG1 |
靶点名称 | SULT2B1 |
抗原物种 | Human |
偶联标记 | Un-conjugated |
別名 | Hydroxysteroid sulfotransferase 2; Alcohol sulfotransferase; Sulfotransferase 2B1; EC 2.8.2.2; HSST2; ST2B1; Sulfotransferase family cytosolic 2B member 1 |
应用说明
应用建议 |
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应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
形式 | Liquid |
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纯化 | Protein A purification |
缓冲液 | PBS with 0.09% sodium azide |
存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
数据库连接 | Swiss-port # O00204 Human Sulfotransferase family cytosolic 2B member 1 |
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基因名称 | SULT2B1 |
全名 | sulfotransferase family, cytosolic, 2B, member 1 |
背景介绍 | Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene sulfates dehydroepiandrosterone but not 4-nitrophenol, a typical substrate for the phenol and estrogen sulfotransferase subfamilies. Two alternatively spliced variants that encode different isoforms have been described. [provided by RefSeq, Jul 2008] |
生物功能 | Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs and xenobiotic compounds. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. Sulfates hydroxysteroids like DHEA. Isoform 1 preferentially sulfonates cholesterol, and isoform 2 avidly sulfonates pregnenolone but not cholesterol. [UniProt] |
预测分子量 | 63 kDa |
检测图片 (3)
ARG44746 anti-SULT2B1 antibody IHC-P image
Immunohistochemistry: Human esophagus stained with ARG44746 anti-SULT2B1 antibody at 5 µg/mL dilution.
ARG44746 anti-SULT2B1 antibody WB image
Western blot: HT29 stained with ARG44746 anti-SULT2B1 antibody at 1 µg/mL dilution.
ARG44746 anti-SULT2B1 antibody IP image
Immunoprecipitation: HT29 lysate immunoprecipitated with 2.5 µg of ARG44746 anti-SULT2B1 antibody.
