anti-SULT2B1 antibody

Key features and details

  • 产品描述: Mouse Monoclonal antibody recognizes SULT2B1
  • 反应物种: Hu
  • 应用: IHC-P, IP, WB
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 同位型: IgG1
  • 靶点名称: SULT2B1
  • 抗原物种: Human
  • 偶联标记: Un-conjugated
  • Brand:
CAT.NO. : ARG44746
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Product Details
概述
产品描述Mouse Monoclonal antibody recognizes SULT2B1
反应物种Hu
应用IHC-P, IP, WB
宿主Mouse
克隆Monoclonal
同位型IgG1
靶点名称SULT2B1
抗原物种Human
偶联标记Un-conjugated
別名Hydroxysteroid sulfotransferase 2; Alcohol sulfotransferase; Sulfotransferase 2B1; EC 2.8.2.2; HSST2; ST2B1; Sulfotransferase family cytosolic 2B member 1
应用说明
应用建议
应用推荐稀释比
IHC-P5-10 µg/mL
IP10 µg/mL
WB1 µg/mL
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Protein A purification
缓冲液PBS with 0.09% sodium azide
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 6820 Human SULT2B1

Swiss-port # O00204 Human Sulfotransferase family cytosolic 2B member 1

基因名称SULT2B1
全名sulfotransferase family, cytosolic, 2B, member 1
背景介绍Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene sulfates dehydroepiandrosterone but not 4-nitrophenol, a typical substrate for the phenol and estrogen sulfotransferase subfamilies. Two alternatively spliced variants that encode different isoforms have been described. [provided by RefSeq, Jul 2008]
生物功能Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs and xenobiotic compounds. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. Sulfates hydroxysteroids like DHEA. Isoform 1 preferentially sulfonates cholesterol, and isoform 2 avidly sulfonates pregnenolone but not cholesterol. [UniProt]
预测分子量63 kDa
检测图片 (3)
  • ARG44746 anti-SULT2B1 antibody IHC-P image

    Immunohistochemistry: Human esophagus stained with ARG44746 anti-SULT2B1 antibody at 5 µg/mL dilution.

  • ARG44746 anti-SULT2B1 antibody WB image

    Western blot: HT29 stained with ARG44746 anti-SULT2B1 antibody at 1 µg/mL dilution.

  • ARG44746 anti-SULT2B1 antibody IP image

    Immunoprecipitation: HT29 lysate immunoprecipitated with 2.5 µg of ARG44746 anti-SULT2B1 antibody.

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