anti-SUR1 / ABCC8 antibody

Key features and details

  • 产品描述: Goat Polyclonal antibody recognizes SUR1 / ABCC8
  • 反应物种: Hu
  • 预测物种: Ms, Rat, Dog
  • 应用: WB
  • 宿主: Goat
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: SUR1 / ABCC8
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG64676
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Product Details
概述
产品描述Goat Polyclonal antibody recognizes SUR1 / ABCC8
反应物种Hu
预测物种Ms, Rat, Dog
应用WB
宿主Goat
克隆Polyclonal
同位型IgG
靶点名称SUR1 / ABCC8
抗原物种Human
抗原C-EFDKPEKLLSRKD
偶联标记Un-conjugated
別名TNDM2; Sulfonylurea receptor 1; ABC36; HHF1; PHHI; ATP-binding cassette sub-family C member 8; MRP8; HI; SUR; SUR1; HRINS; SUR1delta2
应用说明
应用建议
应用推荐稀释比
WB0.5 - 1.5 µg/ml
应用说明WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
缓冲液Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
抗菌剂0.02% Sodium azide
稳定剂0.5% BSA
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 6833 Human ABCC8

Swiss-port # Q09428 Human ATP-binding cassette sub-family C member 8

背景介绍The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a modulator of ATP-sensitive potassium channels and insulin release. Mutations and deficiencies in this protein have been observed in patients with hyperinsulinemic hypoglycemia of infancy, an autosomal recessive disorder of unregulated and high insulin secretion. Mutations have also been associated with non-insulin-dependent diabetes mellitus type II, an autosomal dominant disease of defective insulin secretion. Alternative splicing of this gene has been observed; however, the transcript variants have not been fully described. [provided by RefSeq, Jul 2008]
研究领域Cancer antibody; Cell Biology and Cellular Response antibody; Metabolism antibody; Signaling Transduction antibody
预测分子量177 kDa
检测图片 (1)
  • ARG64676 anti-SUR1 / ABCC8 antibody WB image

    Western Blot: Human Cerebellum lysate (35 µg protein in RIPA buffer) stained with ARG64676 anti-SUR1 / ABCC8 antibody at 0.5 µg/ml dilution.

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