anti-SUR1 / ABCC8 antibody [S289-16]

Key features and details

  • 产品描述: Mouse Monoclonal antibody [S289-16] recognizes SUR1 / ABCC8
  • 反应物种: Ms, Rat
  • 预测物种: Hu, Hm
  • 应用: ICC/IF, IHC-Fr, IHC-P, WB
  • 特异性: Does not cross-react with SUR2B.
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 克隆号: S289-16
  • 同位型: IgG1
  • Brand:
CAT.NO. : ARG22616
US$ Please choose
US$ Please choose
Size:
Trail, Bulk size or Custom requests Please contact us
*产品价格可能会有所调整,请以品牌方官网实时更新的价格为准,以确保准确性。
Product Details
概述
产品描述Mouse Monoclonal antibody [S289-16] recognizes SUR1 / ABCC8
反应物种Ms, Rat
预测物种Hu, Hm
应用ICC/IF, IHC-Fr, IHC-P, WB
特异性Does not cross-react with SUR2B.
宿主Mouse
克隆Monoclonal
克隆号S289-16
同位型IgG1
靶点名称SUR1 / ABCC8
抗原物种Rat
抗原Fusion protein around aa. 1548-1582 (cytoplasmic C-terminus) of Rat SUR1 / ABCC8.
偶联标记Un-conjugated
別名TNDM2; Sulfonylurea receptor 1; ABC36; HHF1; PHHI; ATP-binding cassette sub-family C member 8; MRP8; HI; SUR; SUR1; HRINS; SUR1delta2
应用说明
应用建议
应用推荐稀释比
ICC/IF1:100
IHC-FrAssay-dependent
IHC-PAssay-dependent
WB1:200 - 1:1000
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purification with Protein G.
缓冲液PBS (pH 7.4), 0.09% Sodium azide and 50% Glycerol.
抗菌剂0.09% Sodium azide
稳定剂50% Glycerol
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 25559 Rat ABCC8

Swiss-port # Q09429 Rat ATP-binding cassette sub-family C member 8

基因名称Abcc8
全名ATP-binding cassette, subfamily C (CFTR/MRP), member 8
背景介绍The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a modulator of ATP-sensitive potassium channels and insulin release. Mutations and deficiencies in this protein have been observed in patients with hyperinsulinemic hypoglycemia of infancy, an autosomal recessive disorder of unregulated and high insulin secretion. Mutations have also been associated with non-insulin-dependent diabetes mellitus type II, an autosomal dominant disease of defective insulin secretion. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2013]
生物功能Subunit of the beta-cell ATP-sensitive potassium channel (KATP). Regulator of ATP-sensitive K(+) channels and insulin release. [UniProt]
预测分子量177 kDa (Rat)
检测图片 (2)
  • ARG22616 anti-SUR1 / ABCC8 antibody [S289-16] ICC/IF image

    Immunofluorescence: SK-N-BE cells fixed by 4% Formaldehyde for 15 min at RT. Cells were stained with ARG22616 anti-SUR1 / ABCC8 antibody [S289-16] at 1:100 dilution for 60 min at RT. Magnification: 60X. (A) DAPI (blue) nuclear stain. (B) Phalloidin Texas Red F-Actin stain. (C) Primary antibody (green). (D) Composite.

  • ARG22616 anti-SUR1 / ABCC8 antibody [S289-16] WB image

    Western blot: 15 µg of Rat brain membrane lysate stained with ARG22616 anti-SUR1 / ABCC8 antibody [S289-16] at 1:200 for 16 hours at 4°C. Block: 2% BSA and 2% Skim Milk in 1X TBST.

New Products
Get in touch with AREX
Name:*
Tel/Phone:*
Company:*
Email:*
Inquiry:
Captcha*
Submitting your email information means that you are willing to receive email information from AREX regarding technology, applications, products, and events. By clicking on the 'unsubscribe' button in the email or by contacting info@arexbio.com You can unsubscribe at any time by sending an email. Regarding your data usage information, please refer to our privacy policy.
© AREX 2024. All Rights Reserved. | 浙ICP备2024113709号-3 Sitemap