anti-Synaptobrevin antibody [SP10]

Key features and details

  • 产品描述: Mouse Monoclonal antibody [SP10] recognizes Synaptobrevin
  • 反应物种: Hu, Ms, Rat, Bov, Hm, Pig, Rb
  • 应用: IHC, WB
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 克隆号: SP10
  • 同位型: IgM
  • 靶点名称: Synaptobrevin
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG52433
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Product Details
概述
产品描述Mouse Monoclonal antibody [SP10] recognizes Synaptobrevin
反应物种Hu, Ms, Rat, Bov, Hm, Pig, Rb
应用IHC, WB
宿主Mouse
克隆Monoclonal
克隆号SP10
同位型IgM
靶点名称Synaptobrevin
抗原物种Human
抗原Synaptic immunoprecipitate (crude) from human brain
偶联标记Un-conjugated
別名Vesicle-associated membrane protein 1; Synaptobrevin-1; SYB1; VAMP-1; SPAX1
应用说明
应用建议
应用推荐稀释比
IHC1:100
WB1:1000
应用说明The antibody is specific for the ~16kDa synaptobrevin protein in Western blots of Rat brain lysate. The antibody has also been demonstRated to work in immunohistochemistry on formalin fixed, vibRatome sections, but does not work on paraffin sections.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化IgM Purified
缓冲液10 mM HEPES (pH 7.5), 150 mM NaCl, 0.1 mg/ml BSA and 50% Glycerol
稳定剂0.1 mg/ml BSA, 50% Glycerol
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 22317 Mouse VAMP1

GeneID: 25624 Rat VAMP1

GeneID: 513621 Bovine VAMP1

基因名称VAMP1/2
全名vesicle-associated membrane protein 1 (synaptobrevin 1)
背景介绍Synaptobrevin (aka VAMP) is an integral membrane protein of synaptic vesicles that plays a major role in the formation of larger SNARE complexes, along with SNAP-25 and syntaxin. Synaptobrevin has been shown to be essential for two fast synapse-specific membrane trafficking processes: fast exocytosis for neurotransmitter release and fast endocytosis that mediates rapid recycling of synaptic vesicles (Deak et al., 2004). Decreased levels of synaptobrevin in human hippocampus and cortex have been correlated with cognitive defects in Alzheimer’s disease (Sze et al., 2000).
研究领域Neuroscience antibody; Signaling Transduction antibody
预测分子量13 kDa
检测图片 (1)
  • ARG52433 anti-Synaptobrevin antibody [SP10] WB image

    Western blot: Rat brain lysate showing specific immunolabeling of the ~ 16k synaptobrevin protein stained with ARG52433 anti-Synaptobrevin antibody [SP10].

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