anti-Talin 2 antibody [53.8]

Key features and details

  • 产品描述: Mouse Monoclonal antibody [53.8] recognizes Talin 2
  • 反应物种: Hu, Ms, Rb
  • 应用: ICC/IF, IHC-Fr, IHC-P, IP, WB
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 克隆号: 53.8
  • 同位型: IgG2b
  • 靶点名称: Talin 2
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG23285
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Product Details
概述
产品描述Mouse Monoclonal antibody [53.8] recognizes Talin 2
反应物种Hu, Ms, Rb
应用ICC/IF, IHC-Fr, IHC-P, IP, WB
宿主Mouse
克隆Monoclonal
克隆号53.8
同位型IgG2b
靶点名称Talin 2
抗原物种Human
抗原Recombinant Mouse Talin 2. (aa. 2300-2542)
偶联标记Un-conjugated
別名Talin-2; ILWEQ
应用说明
应用建议
应用推荐稀释比
ICC/IFAssay-dependent
IHC-FrAssay-dependent
IHC-P1:25 - 1:100
IPAssay-dependent
WBAssay-dependent
应用说明ICC/IF: Methanol treatment is required prior to antibody staining.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purification with Protein G.
缓冲液PBS and 0.09% Sodium azide.
抗菌剂0.09% Sodium azide
浓度1 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 70549 Mouse TLN2

GeneID: 83660 Human TLN2

Swiss-port # Q71LX4 Mouse Talin-2

Swiss-port # Q9Y4G6 Human Talin-2

基因名称TLN2
全名talin 2
背景介绍This gene encodes a protein related to talin 1, a cytoskeletal protein that plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. This protein has a different pattern of expression compared to talin 1 but, like talin 1, is thought to associate with unique transmembrane receptors to form novel linkages between extracellular matrices and the actin cytoskeleton. [provided by RefSeq, Jul 2008]
生物功能As a major component of focal adhesion plaques that links integrin to the actin cytoskeleton, may play an important role in cell adhesion. Recruits PIP5K1C to focal adhesion plaques and strongly activates its kinase activity (By similarity). [UniProt]
预测分子量272 kDa
检测图片 (4)
  • ARG23285 anti-Talin 2 antibody [53.8] ICC/IF image

    Immunofluorescence: ARG23285 anti-Talin 2 antibody [53.8] used for immunofluorescent staining of isolated talin-1 null cells fixed in paraformaldehyde and permeablized with triton X-100.

  • ARG23285 anti-Talin 2 antibody [53.8] IHC-Fr image

    Immunohistochemistry: Frozen section of murine heart stained with ARG23285 anti-Talin 2 antibody [53.8].

  • ARG23285 anti-Talin 2 antibody [53.8] WB image

    Western blot: Recombinant talin1 and talin2 proteins stained with ARG23285 anti-Talin 2 antibody [53.8].

  • ARG23285 anti-Talin 2 antibody [53.8] WB image

    Western blot: Murine tissue lysates: Brain, heart, spleen, kidney, lung, liver and muscle lysates stained with ARG23285 anti-Talin 2 antibody [53.8].

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