anti-TCR alpha + beta antibody [IP26]

Key features and details

  • 产品描述: Mouse Monoclonal antibody [IP26] recognizes TCR alpha + beta
  • 反应物种: Hu
  • 应用: CyTOF®-candidate, FACS
  • 特异性: The clone IP26 recognizes a monomorphic determinant of TCR alpha/beta, the dominant subtype of T cell receptor expressed in human peripheral blood.
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 克隆号: IP26
  • 同位型: IgG1
  • 靶点名称: TCR alpha + beta
  • Brand:
CAT.NO. : ARG63107
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Product Details
概述
产品描述Mouse Monoclonal antibody [IP26] recognizes TCR alpha + beta
反应物种Hu
应用CyTOF®-candidate, FACS
特异性The clone IP26 recognizes a monomorphic determinant of TCR alpha/beta, the dominant subtype of T cell receptor expressed in human peripheral blood.
宿主Mouse
克隆Monoclonal
克隆号IP26
同位型IgG1
靶点名称TCR alpha + beta
偶联标记Un-conjugated
应用说明
应用建议
应用推荐稀释比
CyTOF®-candidateAssay-dependent
FACS2 - 4 µg/ml
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照FACS: Human peripheral blood T cells
属性
形式Liquid
纯化Purified from ascites by protein-A affinity chromatography.
纯度> 95% (by SDS-PAGE)
缓冲液PBS (pH 7.4) and 15 mM Sodium azide
抗菌剂15 mM Sodium azide
浓度1 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 6955 Human TRA

背景介绍The antigen-specific T cell receptor (TCR) is composed of either alpha and beta subunit, or gamma and delta subunit. Majority of T cells present in the blood, lymph and secondary lymphoid organs express TCR alpha/beta heterodimers, whereas the T cells expressing TCR gamma/delta heterodimers are localized mainly in epithelial tissues and at the sites of infection. The subunits of TCR heterodimers are covalently bonded and in the endoplasmic reticulum they associate with CD3 subunits to form functional TCR-CD3 complex. Lack of expression of any of the chains is sufficient to stop cell surface expression._x000D_
产品亮点Related products:
TCR antibodies; TCR Duos / Panels; Anti-Mouse IgG secondary antibodies;
Related news:
CyTOF-candidate Antibodies
研究领域Developmental Biology antibody; Immune System antibody
预测分子量TCR alpha: 30 kDa
TCR beta: 35 kDa
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