anti-TCR Cbeta1 antibody [JOVI.1] (PE-Cyanine 5.5)
CAT.NO. : ARG44603
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概述
| 产品描述 | PE-Cyanine 5.5-conjugated Mouse Monoclonal antibody recognizes TCR Cbeta1 |
|---|---|
| 反应物种 | Hu |
| 应用 | FACS |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | JOVI.1 |
| 同位型 | IgG2a kappa |
| 靶点名称 | TCR Cbeta1 |
| 抗原物种 | Human |
| 抗原 | thymus, spleen, and mesenteric lymph nodes isolated from a mouse transgenic for human TCR Vbeta3Cbeta1 |
| 偶联标记 | PE-Cyanine 5.5 |
| 別名 | TRBC1; T Cell Receptor Beta Constant 1; BV05S1J2.2; TCRBC1; V_segment Translation Product; TCRB |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified antibody is conjugated with activated tandem dye of activated Peridinin-Chlorophyll Protein-Cyanine 5.5 (PerCP-Cy™5.5), and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography. |
| 缓冲液 | PBS (pH 7.4) and 15 mM Sodium azide |
| 存放说明 | Aliquot and store in the dark at 2-8°C. Keep protected from prolonged exposure to light. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | TRBC1 |
| 全名 | T Cell Receptor Beta Constant 1 |
| 背景介绍 | Predicted to enable antigen binding activity and immunoglobulin receptor binding activity. Predicted to be involved in several processes, including activation of immune response; defense response to other organism; and phagocytosis. Predicted to be located in plasma membrane. Predicted to be part of immunoglobulin complex, circulating. Predicted to be active in external side of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022] |
| 生物功能 | The T cell repertoire is generated in the thymus, by V-(D)-J rearrangement. This repertoire is then shaped by intrathymic selection events to generate a peripheral T cell pool of self-MH restricted, non-autoaggressive T cells. Post-thymic interaction of alpha-beta TR with the pMH complexes shapes TR structural and functional avidity. [UniProt] |
| 细胞定位 | Cell membrane, Membrane, T cell receptor. [UniProt] |
| 预测分子量 | 20 kDa |
| 翻译后修饰 | Disulfide bond, Glycoprotein. [UniProt] |
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