anti-TCTN3 antibody

Key features and details

  • 产品描述: Rabbit Polyclonal antibody recognizes TCTN3
  • 反应物种: Hu, Ms, Rat
  • 应用: ELISA, ICC/IF, IHC, WB
  • 宿主: Rabbit
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: TCTN3
  • 抗原: Synthetic peptide (17 aa) within aa. 540-590 of Human TCTN3.
  • 偶联标记: Un-conjugated
  • Brand:
CAT.NO. : ARG54663
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Product Details
概述
产品描述Rabbit Polyclonal antibody recognizes TCTN3
反应物种Hu, Ms, Rat
应用ELISA, ICC/IF, IHC, WB
宿主Rabbit
克隆Polyclonal
同位型IgG
靶点名称TCTN3
抗原Synthetic peptide (17 aa) within aa. 540-590 of Human TCTN3.
偶联标记Un-conjugated
別名Tectonic-3; TECT3; C10orf61; JBTS18; OFD4
应用说明
应用建议
应用推荐稀释比
ELISAAssay-Dependent
ICC/IF20 μg/mL
IHC4 μg/mL
WB1 - 2 μg/mL
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
阳性对照SK-N-SH Cell Lysate
属性
形式Liquid
纯化Affinity purification with immunogen.
缓冲液PBS and 0.02% Sodium azide
抗菌剂0.02% Sodium azide
浓度1 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 26123 Human TCTN3

GeneID: 67590 Mouse TCTN3

Swiss-port # Q6NUS6 Human Tectonic-3

Swiss-port # Q8R2Q6 Mouse Tectonic-3

基因名称TCTN3
全名tectonic family member 3
背景介绍TCTN3 Antibody: TCTN3 is a member of the Tectonic protein family, a group of evolutionarily conserved secreted and transmembrane proteins that regulate the Hedgehog (Hh)-mediated patterning of the neural tube. While the expression pattern and function of TCTN3 is not known, it is 58% similar to TCTN1. TCTN1 is expressed during embryonic development in regions that participate in Hh signaling, beginning in the gastrulation stages in the ventral node. Mice expressing mutant TCTN1 die between E13.5 and E16.5 and display holoprosencephaly, a defect associated with reduced Hh signaling, indicating the role of TCTN1 as an Hh activator. At later stages in development, TCTN1 is thought to also act as a repressor on the Hh pathway in the anterior and posterior neural tube. |
研究领域Cell Biology and Cellular Response antibody; Cell Death antibody
预测分子量66 kDa
检测图片 (3)
  • ARG54663 anti-TCTN3 antibody ICC/IF image

    Immunocytochemistry: HeLa cells stained with ARG54663 anti-TCTN3 antibody at 4 μg/ml.

  • ARG54663 anti-TCTN3 antibody ICC/IF image

    Immunofluorescence: HeLa cells stained with ARG54663 anti-TCTN3 antibody at 20 μg/ml.

  • ARG54663 anti-TCTN3 antibody WB image

    Western blot: HeLa cell lysate stained with ARG54663 anti-TCTN3 antibody at (A) 1 and (B) 2μg/ml.

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