anti-TEAD2 antibody
Key features and details
- 产品描述:
- 反应物种:
- 预测物种:
- 应用:
- 特异性:
- 宿主:
- 克隆:
- 同位型:
- 靶点名称:
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Brand:
CAT.NO. : ARG64894
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Product Details
概述
| 产品描述 | Goat Polyclonal antibody recognizes TEAD2 |
|---|---|
| 反应物种 | Hu |
| 预测物种 | Ms, Rat, Cow, Dog |
| 应用 | WB |
| 特异性 | This antibody is not expected to cross-react with other TEAD proteins. |
| 宿主 | Goat |
| 克隆 | Polyclonal |
| 同位型 | IgG |
| 靶点名称 | TEAD2 |
| 抗原物种 | Human |
| 抗原 | C-EPPDAVDSYQRH |
| 偶联标记 | Un-conjugated |
| 別名 | TEA domain family member 2; TEAD-2; TEF-4; ETF; TEF4; Transcriptional enhancer factor TEF-4 |
应用说明
| 应用建议 |
| ||||
|---|---|---|---|---|---|
| 应用说明 | WB: Recommend incubate at RT for 1h. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| 缓冲液 | Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA |
| 抗菌剂 | 0.02% Sodium azide |
| 稳定剂 | 0.5% BSA |
| 浓度 | 0.5 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # Q15562 Human Transcriptional enhancer factor TEF-4 |
|---|---|
| 基因名称 | TEAD2 |
| 全名 | TEA domain family member 2 |
| 生物功能 | Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds to the SPH and GT-IIC 'enhansons' (5'-GTGGAATGT-3'). May be involved in the gene regulation of neural development. Binds to the M-CAT motif. [UniProt] |
| 研究领域 | Gene Regulation antibody |
| 预测分子量 | 49 kDa |
检测图片 (2)
ARG64894 anti-TEAD2 antibody WB image
Western blot: 35 µg of Human Ileum lysate (in RIPA buffer) stained with ARG64894 anti-TEAD2 antibody at 1 µg/ml dilution and incubated at RT for 1 hour.
ARG64894 anti-TEAD2 antibody WB image
Western blot: 35 µg of Human colon lysate (in RIPA buffer) stained with ARG64894 anti-TEAD2 antibody at 1 µg/ml dilution and incubated at RT for 1 hour.
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