anti-Tenascin C antibody [T2H5]
![anti-Tenascin C antibody [T2H5]](/upload/image/products/T2H5_1_210_205.jpg)
![anti-Tenascin C antibody [T2H5]](/upload/image/products/T2H5_1.jpg)
Key features and details
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- 应用:
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- 宿主:
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- 靶点名称:
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Brand:
CAT.NO. : ARG63110
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Product Details
概述
| 产品描述 | Mouse Monoclonal antibody [T2H5] recognizes Tenascin C |
|---|---|
| 反应物种 | Hu |
| 应用 | ICC/IF, IHC-Fr, IHC-P, IP, WB |
| 特异性 | The clone T2H5 recognizes Tenascin C, a large hexameric extracellular matrix glycoprotein. |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | T2H5 |
| 同位型 | IgG1 |
| 靶点名称 | Tenascin C |
| 抗原物种 | Human |
| 抗原 | Protein preparation from a homogenate of a human mammary tumour specimen. |
| 偶联标记 | Un-conjugated |
| 別名 | Cytotactin; HXB; DFNA56; Myotendinous antigen; Hexabrachion; GP; Tenascin-C; Neuronectin; GMEM; TN; 150-225; JI; TN-C; GP 150-225; Glioma-associated-extracellular matrix antigen; Tenascin |
应用说明
| 应用建议 |
| ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | IHC-P: Perform heat mediated antigen retrieval before IHC-P staining step. * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Purified from hybridoma culture supernatant by protein-A affinity chromatography. |
| 纯度 | > 95% (by SDS-PAGE) |
| 缓冲液 | TBS (pH 8.0) and 15 mM Sodium azide |
| 抗菌剂 | 15 mM Sodium azide |
| 浓度 | 1 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | |
|---|---|
| 基因名称 | TNC |
| 全名 | tenascin C |
| 背景介绍 | This gene encodes an extracellular matrix protein with a spatially and temporally restricted tissue distribution. This protein is homohexameric with disulfide-linked subunits, and contains multiple EGF-like and fibronectin type-III domains. It is implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity, and neuronal regeneration. [provided by RefSeq, Jul 2011] |
| 生物功能 | Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown on a monolayer of astrocytes. Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha-V/beta-6. [UniProt] |
| 研究领域 | Signaling Transduction antibody |
| 预测分子量 | 241 kDa |
检测图片 (1)
ARG63110 anti-Tenascin C antibody [T2H5] IHC-P image
Immunohistochemistry: Paraffin-embedded Human tonsil tissue stained with ARG63110 anti-Tenascin C antibody [T2H5].
参考文献
克隆号文献
Lung fibrotic tenascin-C upregulation is associated with other extracellular matrix proteins and induced by TGFβ1.
WB, IHC-P / Human
Tenascin-C is an innate broad-spectrum, HIV-1-neutralizing protein in breast milk.
WB /
Can lineage-specific markers be identified to characterize mesenchyme-derived cell populations in the human airways?
ICC/IF / Human
Tenascin-C as a prognostic biomarker in osteosarcoma?
IHC-P / Human
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