anti-TFIIB antibody [IIB8]
![anti-TFIIB antibody [IIB8]](/upload/image/20241105/8415bc38bc270b898ee2a90369a6c7fb.jpg)
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CAT.NO. : ARG54637
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Product Details
概述
| 产品描述 | Mouse Monoclonal antibody [IIB8] recognizes TFIIB |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | ELISA, EMSA, WB |
| 特异性 | This antibody recognizes an epitopewithin amino acids 52-105 of humanand mouse TFIIB. |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | IIB8 |
| 同位型 | IgG2a |
| 靶点名称 | TFIIB |
| 抗原物种 | Human |
| 抗原 | Partially purified recombinanthuman transcription factor IIB ( |
| 偶联标记 | Un-conjugated |
| 別名 | Transcription initiation factor IIB; General transcription factor TFIIB; TF2B; TFIIB; S300-II |
应用说明
| 应用建议 |
| ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
属性
| 形式 | Liquid |
|---|---|
| 纯化 | Protein G affinity chromatography |
| 缓冲液 | PBS (pH 7.4) |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
生物信息
| 数据库连接 | Swiss-port # P62915 Mouse Transcription initiation factor IIB Swiss-port # Q00403 Human Transcription initiation factor IIB |
|---|---|
| 基因名称 | GTF2B |
| 全名 | general transcription factor IIB |
| 背景介绍 | This gene encodes the general transcription factor IIB, one of the ubiquitous factors required for transcription initiation by RNA polymerase II. The protein localizes to the nucleus where it forms a complex (the DAB complex) with transcription factors IID and IIA. Transcription factor IIB serves as a bridge between IID, the factor which initially recognizes the promoter sequence, and RNA polymerase II. [provided by RefSeq, Jul 2008] |
| 生物功能 | General factor that plays a major role in the activation of eukaryotic genes transcribed by RNA polymerase II. [UniProt] |
| 研究领域 | Gene Regulation antibody |
| 预测分子量 | 35 kDa |
参考文献
克隆号文献
Protection against oxidative stress through SUA7/TFIIB regulation in Saccharomyces cerevisiae.
WB / Saccharomyces cerevisiae
Purification of recombinant human transcription factor IIB by immunoaffinity chromatography.
Accessibility of epitopes on human transcription factor IIB in the native protein and in a complex with DNA.
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