anti-TGN46 antibody

Key features and details

  • 产品描述: Sheep Polyclonal antibody recognizes TGN46This antibody recognizes Trans-Golgi network integral membrane protein 2 (TGOLN2), also known as TGN38 homolog, TGN46, TGN48 or Trans-Golgi network protein TGN51. TGN46 is a 437 amino acid glycoprotein localized to the Trans-Golgi network. TGN46 has been reported as being the best available marker for human trans-Golgi network.TGN46 is a heavily glycosylated protein of around 110-120 kDa. Multiple isoforms of TGN46 are generated by alternative splicing difffering in sequence at the C-terminal protion. Sheep anti Human TGN46 antibody is expeced to recognize all identified isoforms.
  • 反应物种: Hu, NHuPrm
  • 应用: ICC/IF, IHC-Fr, WB
  • 宿主: Sheep
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: TGN46
  • 抗原物种: Human
  • 抗原: Recombinant human TGN46.
  • Brand:
CAT.NO. : ARG22416
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Product Details
概述
产品描述Sheep Polyclonal antibody recognizes TGN46
This antibody recognizes Trans-Golgi network integral membrane protein 2 (TGOLN2), also known as TGN38 homolog, TGN46, TGN48 or Trans-Golgi network protein TGN51. TGN46 is a 437 amino acid glycoprotein localized to the Trans-Golgi network. TGN46 has been reported as being the best available marker for human trans-Golgi network.TGN46 is a heavily glycosylated protein of around 110-120 kDa. Multiple isoforms of TGN46 are generated by alternative splicing difffering in sequence at the C-terminal protion. Sheep anti Human TGN46 antibody is expeced to recognize all identified isoforms.
反应物种Hu, NHuPrm
应用ICC/IF, IHC-Fr, WB
宿主Sheep
克隆Polyclonal
同位型IgG
靶点名称TGN46
抗原物种Human
抗原Recombinant human TGN46.
偶联标记Un-conjugated
別名Trans-Golgi network protein TGN51; TGN48; TGN46; TGN51; Trans-Golgi network integral membrane protein 2; TGN38 homolog; TTGN2; TGN38
应用说明
应用建议
应用推荐稀释比
ICC/IFAssay-dependent
IHC-Fr1:50 - 1:100
WB1:500 - 1:000
应用说明IHC-Fr: Fixation with 3% paraformaldehyde or methanol/acetone is recommended.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Affinity purified.
缓冲液PBS, 0.02% Sodium azide, 25% Glycerol and 1% BSA.
抗菌剂0.02% Sodium azide
稳定剂25% Glycerol and 1% BSA
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 10618 Human TGOLN2

Swiss-port # O43493 Human Trans-Golgi network integral membrane protein 2

基因名称TGOLN2
全名trans-golgi network protein 2
背景介绍This gene encodes a type I integral membrane protein that is localized to the trans-Golgi network, a major sorting station for secretory and membrane proteins. The encoded protein cycles between early endosomes and the trans-Golgi network, and may play a role in exocytic vesicle formation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]
生物功能May be involved in regulating membrane traffic to and from trans-Golgi network. [UniProt]
预测分子量46 kDa (unmodified). 110-120 kDa (glycosylated)
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