anti-Themis antibody

Key features and details

  • 产品描述: Goat Polyclonal antibody recognizes Themis
  • 反应物种: Ms
  • 应用: WB
  • 宿主: Goat
  • 克隆: Polyclonal
  • 同位型: IgG
  • 靶点名称: Themis
  • 抗原物种: Mouse
  • 抗原: C-EERTINLPKSLKSH
  • Brand:
CAT.NO. : ARG65187
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Product Details
概述
产品描述Goat Polyclonal antibody recognizes Themis
反应物种Ms
应用WB
宿主Goat
克隆Polyclonal
同位型IgG
靶点名称Themis
抗原物种Mouse
抗原C-EERTINLPKSLKSH
偶联标记Un-conjugated
別名C6orf207; C6orf190; SPOT; Thymocyte-expressed molecule involved in selection; bA325O24.3; Protein THEMIS; bA325O24.4; GASP; TSEPA
应用说明
应用建议
应用推荐稀释比
WB1 - 3 µg/ml
应用说明WB: Recommend incubate at RT for 1h.
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
缓冲液Tris saline (pH 7.3), 0.02% Sodium azide and 0.5% BSA
抗菌剂0.02% Sodium azide
稳定剂0.5% BSA
浓度0.5 mg/ml
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 210757 Mouse THEMIS

Swiss-port # Q8BGW0 Mouse Protein THEMIS

基因名称Themis
全名thymocyte selection associated
背景介绍This gene encodes a protein that plays a regulatory role in both positive and negative T-cell selection during late thymocyte development. The protein functions through T-cell antigen receptor signaling, and is necessary for proper lineage commitment and maturation of T-cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]
生物功能Plays a central role in late thymocyte development by controlling both positive and negative T-cell selection. Required to sustain and/or integrate signals required for proper lineage commitment and maturation of T-cells. Regulates T-cell development through T-cell antigen receptor (TCR) signaling and in particular through the regulation of calcium influx and phosphorylation of Erk. [UniProt]
研究领域Developmental Biology antibody; Immune System antibody
预测分子量73 kDa
翻译后修饰Phosphorylated on Tyr residues quickly after TCR stimulation.
检测图片 (1)
  • ARG65187 anti-Themis antibody WB image

    Western Blot: Mouse Spleen lysate (35 µg protein in RIPA buffer) stained with ARG65187 anti-Themis antibody at 0.3 µg/ml dilution.

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