anti-THOP1 / Thimet Oligopeptidase antibody

Key features and details

  • 产品描述: Mouse Monoclonal antibody recognizes THOP1 / Thimet Oligopeptidase
  • 反应物种: Hu
  • 应用: IP
  • 宿主: Mouse
  • 克隆: Monoclonal
  • 同位型: IgG2a
  • 靶点名称: THOP1 / Thimet Oligopeptidase
  • 抗原物种: Human
  • 偶联标记: Un-conjugated
  • Brand:
CAT.NO. : ARG44752
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Product Details
概述
产品描述Mouse Monoclonal antibody recognizes THOP1 / Thimet Oligopeptidase
反应物种Hu
应用IP
宿主Mouse
克隆Monoclonal
同位型IgG2a
靶点名称THOP1 / Thimet Oligopeptidase
抗原物种Human
偶联标记Un-conjugated
別名EP24.15; TOP; Thimet oligopeptidase; MEPD_HUMAN; EC 3.4.24.15; Endopeptidase 24.15; MP78
应用说明
应用建议
应用推荐稀释比
IP10 µg/mL
应用说明* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Protein A purification
缓冲液PBS with 0.09% sodium azide
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 7064 Human THOP1

Swiss-port # P52888 Human Thimet oligopeptidase

基因名称THOP1
全名thimet oligopeptidase 1
生物功能Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle. Together with the CITED2 coactivator, stimulates the PITX2 P1 promoter transcription activation. Associates with chromatin to the PITX2 P1 promoter region. [UniProt]
细胞定位Cytoplasm. [UniProt]
预测分子量79 kDa
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