anti-Thymidine Phosphorylase antibody [P-GF.44C]
![anti-Thymidine Phosphorylase antibody [P-GF.44C]](/upload/image/20241105/8415bc38bc270b898ee2a90369a6c7fb.jpg)
Key features and details
- 产品描述:
- 反应物种:
- 应用:
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- 靶点名称:
- 抗原物种:
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Product Details
| 产品描述 | Mouse Monoclonal antibody [P-GF.44C] recognizes Thymidine Phosphorylase |
|---|---|
| 反应物种 | Hu, Ms |
| 应用 | FACS, IHC-Fr, IHC-P, IP, WB |
| 宿主 | Mouse |
| 克隆 | Monoclonal |
| 克隆号 | P-GF.44C |
| 同位型 | IgG1 |
| 靶点名称 | Thymidine Phosphorylase |
| 抗原物种 | Human |
| 抗原 | Recombinant full length human thymidine phosphorylase (TP/ PD-ECGF) protein |
| 偶联标记 | Un-conjugated |
| 別名 | MEDPS1; MTDPS1; ECGF; Gliostatin; EC 2.4.2.4; TP; PD-ECGF; TdRPase; MNGIE; ECGF1; hPD-ECGF; Platelet-derived endothelial cell growth factor; PDECGF; Thymidine phosphorylase |
| 应用说明 | * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist. |
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| 阳性对照 | Breast carcinoma, HUVEC cells |
| 形式 | Liquid |
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| 缓冲液 | 10mM PBS (pH 7.4), 0.2% BSA and 0.09% Sodium azide |
| 抗菌剂 | 0.09% Sodium azide |
| 稳定剂 | 0.2% BSA |
| 浓度 | 0.2 mg/ml |
| 存放说明 | For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use. |
| 注意事项 | For laboratory research only, not for drug, diagnostic or other use. |
| 数据库连接 | |
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| 基因名称 | TYMP |
| 全名 | thymidine phosphorylase |
| 背景介绍 | This gene encodes an angiogenic factor which promotes angiogenesis in vivo and stimulates the in vitro growth of a variety of endothelial cells. It has a highly restricted target cell specificity acting only on endothelial cells. Mutations in this gene have been associated with mitochondrial neurogastrointestinal encephalomyopathy. Multiple alternatively spliced transcript variants have been identified. [provided by RefSeq, Apr 2012] |
| 生物功能 | May have a role in maintaining the integrity of the blood vessels. Has growth promoting activity on endothelial cells, angiogenic activity in vivo and chemotactic activity on endothelial cells in vitro. Catalyzes the reversible phosphorolysis of thymidine. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. [UniProt] |
| 研究领域 | Cell Biology and Cellular Response antibody; Cell Death antibody; Gene Regulation antibody; Signaling Transduction antibody |
| 预测分子量 | 50 kDa |
克隆号文献
Inhibition of EGFR phosphorylation in a panel of human breast cancer cells correlates with synergistic interactions between gefitinib and 5'-DFUR, the bioactive metabolite of Xeloda.
Thymidine synthase, thymidine phosphorylase, and excision repair cross-complementation group 1 expression as predictive markers of capecitabine plus cisplatin chemotherapy as first-line treatment for patients with advanced oesophageal squamous cell carcinoma.
IHC / Human
Angiopoietin-2 regulates gene expression in TIE2-expressing monocytes and augments their inherent proangiogenic functions.
WB, IHC-Fr / Human, Mouse
Enhanced interferon signaling pathway in oral cancer revealed by quantitative proteome analysis of microdissected specimens using 16O/18O labeling and integrated two-dimensional LC-ESI-MALDI tandem MS.
WB / Human
Characterization of a novel TYMP splice site mutation associated with mitochondrial neurogastrointestinal encephalomyopathy (MNGIE).
WB / Human
Neoadjuvant treatment of colorectal cancer with bevacizumab: the perioperative angiogenic balance is sensitive to systemic thrombospondin-1 levels.
ELISA / Human
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