anti-TIGIT antibody [4A11]

CAT.NO. : ARG57744

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Size:

50 μg

*产品价格可能会有所调整，请以品牌方官网实时更新的价格为准，以确保准确性。

Product Details

概述

产品描述	Mouse Monoclonal antibody [4A11] recognizes TIGIT
反应物种	Hu
应用	FACS, ICC/IF, IHC-P, WB
宿主	Mouse
克隆	Monoclonal
同位型	IgG1
靶点名称	TIGIT
抗原物种	Human
抗原	Synthetic peptide around the extracellular domain of Human TIGIT.
偶联标记	Un-conjugated
別名	TIGIT; T Cell Immunoreceptor With Ig And ITIM Domains; VSIG9; VSTM3; V-Set And Immunoglobulin Domain-Containing Protein 9; V-Set And Transmembrane Domain-Containing Protein 3; T-Cell Immunoreceptor With Ig And ITIM Domains; DKFZp667A205; VSIG9, VSTM3; FLJ39873; V-Set And Immunoglobulin Domain Containing 9; Washington University Cell Adhesion Molecule 3; V-Set And Transmembrane Domain Containing 3; WUCAM

应用说明

应用建议

应用说明

* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

属性

形式	Liquid
纯化	Purification with Protein A.
缓冲液	PBS and 0.02% Sodium azide.
抗菌剂	0.02% Sodium azide
浓度	1 mg/ml
存放说明	For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C or below. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项	For laboratory research only, not for drug, diagnostic or other use.

生物信息

数据库连接	GeneID: 201633 Human TIGIT Swiss-port # Q495A1 Human T-cell immunoreceptor with Ig and ITIM domains
基因名称	TIGIT
全名	T cell immunoreceptor with Ig and ITIM domains
背景介绍	This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.
生物功能	Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells.
细胞定位	Cell membrane, Membrane
预测分子量	26 kDa
翻译后修饰	Disulfide bond, Glycoprotein

检测图片 (6)

ARG57744 anti-TIGIT antibody [4A11] ICC/IF image
Immunocytochemistry: TIGIT over expressing HEK293 cells stained with ARG57744 anti-TIGIT antibody [4A11] and control Mouse IgG antibody (corner box) at 1 µg/ml dilution.
ARG57744 anti-TIGIT antibody [4A11] FACS image
Flow Cytometry: Untransfected (blue) and TIGIT over expressing HEK293 cells (yellow) stained with ARG57744 anti-TIGIT antibody [4A11] at 1 µg/ml dilution.
ARG57744 anti-TIGIT antibody [4A11] IHC-P image
Immunohistochemistry: Paraffin-embedded Human stomach carcinoma tissue stained with ARG57744 anti-TIGIT antibody [4A11] and control Mouse IgG (corner box) at 2 µg/ml dilution.
ARG57744 anti-TIGIT antibody [4A11] WB image
Western blot: TIGIT over expressing HEK293 cells stained with ARG57744 anti-TIGIT antibody [4A11] at 0.25, 0.5 or 1 µg/ml dilution.
ARG57744 anti-TIGIT antibody [4A11] ICC/IF image
Immunofluorescence: TIGIT over expressing HEK293 cells stained with ARG57744 anti-TIGIT antibody [4A11] at 1 µg/ml dilution.
ARG57744 anti-TIGIT antibody [4A11] IHC image
Immunohistochemistry: Human stomach carcinoma tissue stained with ARG57744 anti-TIGIT antibody [4A11] at 5 µg/ml dilution.

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