anti-TIGIT antibody [SQab30360]

Key features and details

  • 产品描述: Recombinant Rabbit Monoclonal antibody [SQab30360] recognizes TIGIT
  • 反应物种: Hu
  • 应用: IHC-P
  • 宿主: Rabbit
  • 克隆: Monoclonal
  • 克隆号: SQab30360
  • 同位型: IgG
  • 靶点名称: TIGIT
  • 抗原物种: Human
  • Brand:
CAT.NO. : ARG67087
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Product Details
概述
产品描述Recombinant Rabbit Monoclonal antibody [SQab30360] recognizes TIGIT
反应物种Hu
应用IHC-P
宿主Rabbit
克隆Monoclonal
克隆号SQab30360
同位型IgG
靶点名称TIGIT
抗原物种Human
抗原Recombinant protein of Human TIGIT.
偶联标记Un-conjugated
別名TIGIT; T Cell Immunoreceptor With Ig And ITIM Domains; VSIG9; VSTM3; V-Set And Immunoglobulin Domain-Containing Protein 9; V-Set And Transmembrane Domain-Containing Protein 3; T-Cell Immunoreceptor With Ig And ITIM Domains; DKFZp667A205; VSIG9, VSTM3; FLJ39873; V-Set And Immunoglobulin Domain Containing 9; Washington University Cell Adhesion Molecule 3; V-Set And Transmembrane Domain Containing 3; WUCAM
应用说明
应用建议
应用推荐稀释比
IHC-P1:100-1:200
应用说明IHC-P: Antigen Retrieval: Heat mediation was performed in Tris/EDTA buffer (pH 9.0).
* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.
属性
形式Liquid
纯化Purification with Protein A.
缓冲液PBS, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA.
抗菌剂0.01% Sodium azide
稳定剂40% Glycerol and 0.05% BSA
存放说明For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.
注意事项For laboratory research only, not for drug, diagnostic or other use.
生物信息
数据库连接

GeneID: 201633 Human TIGIT

Swiss-port # Q495A1 Human T-cell immunoreceptor with Ig and ITIM domains

基因名称TIGIT
全名T Cell Immunoreceptor With Ig And ITIM Domains
背景介绍This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.
生物功能Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells.
细胞定位Cell membrane, Membrane
预测分子量26 kDa
翻译后修饰Disulfide bond, Glycoprotein
检测图片 (1)
  • ARG67087 anti-TIGIT antibody [SQab30360] IHC-P image

    Immunohistochemistry: Human tonsil stained with ARG67087 anti-TIGIT antibody [SQab30360]

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